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Using blinking to measure Parkinson's symptoms

Researchers are using a high-speed camera and computer analysis to investigate whether blinking reflects movement symptoms.

Learning by observing or collecting information · Study reference: TCTR20190817003

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Start (reported date)
2019-08-22
Study finished (reported date)
2021-01-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 80 years · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: Normal healthy volunteers (90) Dry eye syndrome (30) Facial Paralysis (30) Other neurologic disorders that affect blink (30) Exclusion criteria: Prior eyelid surgery Prior eyelid trauma Vision worse than 20/200 Inconclusive clinical diagnosis
Full study name & original research details

Official study title

A non-invasive method to analyze spontaneous blink using high-speed camera and machine learning approach

Original description

Intervention: 90 subjects without eye diseases that affect blinks 1.1) Age 18-39 y, 30 subjects 1.2) Age 40-59 y, 30 subjects 1.3) Age 60-80 y, 30 subjects,e.g. Parkinson's disease, blepharospasm 30 subjects,30 subjects with clinical diagnosis of facial paralysis,30 subjects with clinical diagnosis of dry eyes;Other,Other,Other,Other;Normal healthy volunteers,Other neurological disorders that affect blink,Facial Paralysis,Dry eye syndrome Primary outcome: Spontaneous blink At the time of measurement ฺBlink rate per minute, blink speed, amplitude/ High-speed camera and machine learning,Mahidol Blink Analyzer 3 years N/A Secondary outcome: Accuracy and Validity of Mahidol Blink Analyzer 3 years N/A

Conditions reported: Normal healthy volunteers Dry eye syndrome Facial Paralysis BlepharospasmParkinson's disease Normal healthy volunteers Dry eye syndrome Facial Paralysis Blepharospasm Parkinson's disease;Normal healthy volunteers Dry eye syndrome Facial Paralysis Blepharospasm Parkinson's disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
90 subjects without eye diseases that affect blinks 1.1) Age 18-39 y, 30 subjects 1.2) Age 40-59 y, 30 subjects 1.3) Age 60-80 y, 30 subjects,e.g. Parkinson's disease, blepharospasm 30 subjects,30 subjects with clinical diagnosis of facial paralysis,30 subjects with clinical diagnosis of dry eyes;Other,Other,Other,Other;Normal healthy volunteers,Other neurological disorders that affect blink,Facial Paralysis,Dry eye syndrome
Phases
Phase 1/Phase 2
Sponsor
Faculty of Medicine Siriraj Hospital, Mahidol University
Start date reported by registry
2019-08-22 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Pimkwan Jaru-ampornpan · 0944199164 · pimkwan.jar@mahidol.edu

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Thailand

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.