Recruiting · registry status

A physiotherapy session when medicines wear off

This study examines balance after physiotherapy during periods when Parkinson's medicines are having less effect.

Testing a treatment or activity · Study reference: RBR-8f32jdb

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Results reported

Start (reported date): 2026-03-05
Study finished (reported date): 2026-08-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

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Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 55y to 90y · Ask the team who can join

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Sex eligibility reported by registry: -

Inclusion criteria: Men and women aged between 55 and 90 years; diagnosis of idiopathic Parkinson’s disease by a neurologist; onset of motor symptoms for at least three years; use of levodopa in at least three daily doses, with or without other antiparkinsonian medications; Hoehn and Yahr stages between 1 and 4; ability to stand and walk; negative responses to all items of the Physical Activity Readiness Questionnaire (PAR-Q) Exclusion criteria: Clinical contraindication to physical exercise; uncontrolled hypertension or hypotension; inability to walk independently; myocardial infarction within the last 12 months; disabling sequelae of stroke; history of brain surgery; use of deep brain stimulation; presence of orthopedic prostheses limiting test performance; diabetic peripheral neuropathy; difficulty understanding or inability to follow simple commands

Full study name & original research details

Official study title

Effects of a Single Session of Proprioceptive Neuromuscular Facilitation on Static and Dynamic Balance in Individuals with Parkinson’s Disease During the OFF Medication State

Short title used by the registry

Effects of a Single Physiotherapy Session on Balance in Individuals with Parkinson’s Disease During the Low Medication Effect Period

Original description

Intervention: This is a two-arm randomized controlled clinical trial single-blind with blinding of the data evaluator. Participants were randomly allocated by drawing lots. Intervention group: 7 participants with Parkinson's disease will receive a single 20-minute session of Proprioceptive Neuromuscular Facilitation (PNF) composed of weight-bearing exercises in an orthostatic position with emphasis on the most affected lower limb followed by static balance training with proprioceptive feedback (verbal commands tactile stimulation and approximation) ending with step training. The intervention will be performed during the OFF period of dopaminergic medication. Control group: 7 participants with Parkinson's disease will perform the same exercises as the intervention group however without the application of the proprioceptive feedback characteristic of the PNF concept (SHAM condition) Primary outcome: It's expected to observe postural balance changes assessed through center of pressure variables obtained from a force platform (displacement amplitude and velocity) during standing task, comparing pre- and post-intervention moments in individuals with Parkinson's disease in the OFF medication state Secondary outcome: It's expected to observe electromyographic activity changes of lower limb muscles assessed through surface electromyography (signal amplitude and activation timing) during standing and gait initiation tasks, comparing pre- and post-intervention moments; it's expected to find changes in anticipatory postural adjustments parameters obtained from electromyographic and force platform variables; it's expected to find changes in kinematic and spatiotemporal variables of gait initiation assessed by accelerometry (reaction time, execution time, and displacement)

Conditions reported: Parkinson Disease Nervous System Diseases

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

REBEC · RBR-8f32jdb ↗ — Recruiting; WHO ICTRP processed 2026-08-03; checked 2026-10-11

Study type: Interventional
Interventions: This is a two-arm randomized controlled clinical trial single-blind with blinding of the data evaluator. Participants were randomly allocated by drawing lots. Intervention group: 7 participants with Parkinson's disease will receive a single 20-minute session of Proprioceptive Neuromuscular Facilitation (PNF) composed of weight-bearing exercises in an orthostatic position with emphasis on the most affected lower limb followed by static balance training with proprioceptive feedback (verbal commands tactile stimulation and approximation) ending with step training. The intervention will be performed during the OFF period of dopaminergic medication. Control group: 7 participants with Parkinson's disease will perform the same exercises as the intervention group however without the application of the proprioceptive feedback characteristic of the PNF concept (SHAM condition)
Phases: N/A
Sponsor: Universidade Federal do Rio Grande do Sul
Start date reported by registry: 2026-03-05 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Flávia Martinez · +55(51)98146-8536 · fla.gmartinez@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.