Recruiting · registry status

Magnetic brain stimulation for voice difficulties

This small study investigates the practicality of stimulation treatment and its effects on voice quality and loudness.

Testing a treatment or activity · Study reference: RBR-8cgtwq5

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Results reported

Start (reported date): 2026-02-27
Study finished (reported date): 2026-08-20

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Changes we have recorded

2026-10-11 — recruiting

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Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18y to 0 · Ask the team who can join

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Sex eligibility reported by registry: -

Inclusion criteria: Patients with vocal and/or speech disorders; diagnosis of idiopathic Parkinson's disease; age over 18 years; able to understand commands Exclusion criteria: Patients with magnetic material in the skull or a cardiac pacemaker; epilepsy; history of seizures; smokers; who have another concomitant neurological condition

Full study name & original research details

Official study title

Non-invasive brain stimulation in neurological conditions

Short title used by the registry

Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on vocal quality and voice intensity in patients with Parkinson's disease: a feasibility study

Original description

Intervention: This is a feasibility study, designed as a case series, linked to the parent project approved in the Brazilian Registry of Clinical Trials (ReBEC – RBR-5s76ksq). In this derivative project, 12 patients of both sexes with idiopathic Parkinson’s disease will be recruited by convenience sampling. Participants may be referred from outpatient services, whether specialized or not, and/or recruited through spontaneous demand, provided they meet the inclusion and exclusion criteria established for a single-group intervention study. All eligible individuals will be allocated to a single experimental group and will undergo treatment with Transcranial Magnetic Stimulation (n = 12), receiving the “active” modality of non-invasive brain stimulation through transcranial magnetic stimulation. Patients with vocal and/or speech impairments, a diagnosis of idiopathic Parkinson’s disease, age over 18 years, and the ability to understand commands will be included. Individuals will be excluded if they have magnetic material in the skull or a cardiac pacemaker; epilepsy or a history of seizures; are smokers; or present another concomitant neurological condition. A total of eight magnetic stimulation sessions will be performed (twice per week for four weeks, on alternating days). During the Transcranial Magnetic Stimulation intervention, patients will also receive specialized speech-language therapy focusing on associated vocal techniques. Each session will last approximately 15 minutes, with stimulation delivered at 10 Hz, 50 pulses per train, 30 trains, and a 20-second inter-train interval, totaling 1,500 pulses per session. Stimulation intensity will be set at 90% of the motor threshold, targeting the motor cortex area (M1–C3/C4) according to the international 10–20 system, using a figure- Primary outcome: The feasibility and safety of applying the procedure are expected to be proven Secondary outcome: An improvement in voice quality and intensity is expected, as assessed by a decrease in acoustic disturbance measures and an increase in vocal emission intensity.

Conditions reported: Parkinson Disease Nervous System Diseases

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

REBEC · RBR-8cgtwq5 ↗ — Recruiting; WHO ICTRP processed 2026-06-01; checked 2026-10-11

Study type: Interventional
Interventions: This is a feasibility study, designed as a case series, linked to the parent project approved in the Brazilian Registry of Clinical Trials (ReBEC – RBR-5s76ksq). In this derivative project, 12 patients of both sexes with idiopathic Parkinson’s disease will be recruited by convenience sampling. Participants may be referred from outpatient services, whether specialized or not, and/or recruited through spontaneous demand, provided they meet the inclusion and exclusion criteria established for a single-group intervention study. All eligible individuals will be allocated to a single experimental group and will undergo treatment with Transcranial Magnetic Stimulation (n = 12), receiving the “active” modality of non-invasive brain stimulation through transcranial magnetic stimulation. Patients with vocal and/or speech impairments, a diagnosis of idiopathic Parkinson’s disease, age over 18 years, and the ability to understand commands will be included. Individuals will be excluded if they have magnetic material in the skull or a cardiac pacemaker; epilepsy or a history of seizures; are smokers; or present another concomitant neurological condition. A total of eight magnetic stimulation sessions will be performed (twice per week for four weeks, on alternating days). During the Transcranial Magnetic Stimulation intervention, patients will also receive specialized speech-language therapy focusing on associated vocal techniques. Each session will last approximately 15 minutes, with stimulation delivered at 10 Hz, 50 pulses per train, 30 trains, and a 20-second inter-train interval, totaling 1,500 pulses per session. Stimulation intensity will be set at 90% of the motor threshold, targeting the motor cortex area (M1–C3/C4) according to the international 10–20 system, using a figure-
Phases: N/A
Sponsor: Centro de Ciências da Saúde da Universidade Federal do Espírito Santo
Start date reported by registry: 2026-02-27 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Carolina Comarela · +55(27)99258-7245 · cfanhoque@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.