Recruiting · registry status

Infrared light applied to the head

Researchers are comparing active and simulated light treatment to investigate its effects in Parkinson's.

Testing a treatment or activity · Study reference: RBR-72hp4v9

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Results reported

Start (reported date): 2024-09-02
Study finished (reported date): 2025-12-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

Read the results reported in the registry

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18y to 60y · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

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Sex eligibility reported by registry: -

Inclusion criteria: As inclusion criteria, volunteers of both genders who are patients diagnosed with Parkinson disease (PD) in stages I to III of the Hoehn and Yahr scale (Shenkman et al., 2001); they must be between 18 and 60 years old; volunteers of both sexes will be accepted; volunteers in the active period must present themselves without severe dyskinesia; they must be able to remain in an upright position, standing still for at least 2 minutes and walk without assistance for 10 meters; free from sensory changes in the head region or inability to communicate with the researcher in any type of eventuality such as emergency situations Exclusion criteria: As for exclusion criteria, participants must not present any neurological condition other than Parkinson disease (PD), such as Alzheimer's disease and other dementias; sequelae of stroke; cognitive insufficiency; delirium; depression; use deep brain stimulators or any other types of brain implants; patients will also be excluded if they have a history of head surgery; cranioplasty; metallic implants; stents; ventriculoperitoneal shunts; hydrocephalus; microcephaly; traumatic brain injury; myelomeningocele; meningocele and any other malformation of the central nervous system

Full study name & original research details

Official study title

Evaluation of the effects of transcranial photobiomodulation in patients with Parkinson´s disease

Short title used by the registry

Evaluation of the effects of overhead infrared light irradiation in patients with Parkinson's disease

Original description

Intervention: This is a controlled, longitudinal, prospective, double-blind, randomized clinical trial, with the sample divided into two groups. The intervention group will consist of 36 patients diagnosed with Parkinson's disease of both sexes and over the age of 18. The control group will have a similar number of patients to the intervention group, all diagnosed with Parkinson's disease who will not undergo intervention with the photobiomodulation technique but will continue with their respective conventional treatments (pharmacological and approaches with physiotherapy, speech therapy and psychology, etc.). The duration of the study is twenty-four weeks distributed from the initial evaluation of the patients until the final reevaluation. The randomization process will be carried out through the Randomizer program. After the initial evaluation, the patient will be identified by a number when he/she will participate in the research and submit to the application made by a professional trained in the technique but who will connect the device in the treatment protocol only in the intervention group. The researcher who will compile and statistically treat the data will not know which patient was treated or was in the control group.;E02.774 Primary outcome: This research is expected to improve the motor function of individuals in the intervention group, as well as improve cognitive function and other non-motor signs and symptoms. Secondary outcome: No secondary outcomes are expected

Conditions reported: Hypokinesia;C10.228.140.079.862.500

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

REBEC · RBR-72hp4v9 ↗ — Recruiting; WHO ICTRP processed 2025-10-27; checked 2026-10-11

Study type: Interventional
Interventions: This is a controlled, longitudinal, prospective, double-blind, randomized clinical trial, with the sample divided into two groups. The intervention group will consist of 36 patients diagnosed with Parkinson's disease of both sexes and over the age of 18. The control group will have a similar number of patients to the intervention group, all diagnosed with Parkinson's disease who will not undergo intervention with the photobiomodulation technique but will continue with their respective conventional treatments (pharmacological and approaches with physiotherapy, speech therapy and psychology, etc.). The duration of the study is twenty-four weeks distributed from the initial evaluation of the patients until the final reevaluation. The randomization process will be carried out through the Randomizer program. After the initial evaluation, the patient will be identified by a number when he/she will participate in the research and submit to the application made by a professional trained in the technique but who will connect the device in the treatment protocol only in the intervention group. The researcher who will compile and statistically treat the data will not know which patient was treated or was in the control group.;E02.774
Phases: N/A
Sponsor: Universidade Federal de Pernambuco
Start date reported by registry: 2024-09-02 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Alexandre da Silva · +55(81) 997983531 · alexandre.roques@ufpe.br

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Brazil

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.