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Immediate effects of a cycling session

Researchers are comparing exercise intensities and measuring thinking and brain blood-vessel responses in Parkinson's.

Testing a treatment or activity · Study reference: RBR-103nyv5v

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Results reported

Start (reported date)
2023-01-02
Study finished (reported date)
2025-03-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

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Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

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Who can join?

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Sex eligibility reported by registry: -

Inclusion criteria: previous diagnosis of Parkinson's Disease; being undergoing pharmacological treatment for Parkinson's Disease; be at least 50 years old Exclusion criteria: being in Hoehn & Yahr stages 4 or 5 of Parkinson's Disease; presenting other neurological diseases in addition to Parkinson's disease; present electrocardiographic alterations during exercise test suggestive of cardiovascular pathology; having a diagnosis of cardiovascular disease, cancer, or any type of dementia; score = 20 on the “Montreal Cognitive Assessment (MoCA)”; be performing aerobic training regularly; have musculoskeletal problems that interfere with performing aerobic exercise
Full study name & original research details

Official study title

Aerobic Exercise effects on cognitive and cerebrovascular functions on patients withParkinson Disease

Short title used by the registry

Effects of an Exercise session performed on stationary bicycle on cognitive function and cerebral blood vessel function in patients with Parkinson's disease

Original description

Intervention: A single group of 18 patients with Parkinson's disease will be submitted to 3 experimental sessions (crossover study) performed in random order: moderate intensity aerobic exercise, high intensity aerobic exercise and control. In all sessions, an intervention period of 30 minutes will be used. In the exercise sessions, patients will exercise on a cycle ergometer. Exercise intensity will correspond to 40-60% of heart rate reserve in the moderate intensity session, and 60-85% of heart rate reserve in the high intensity session. In the control session, patients will remain seated at rest.;G11.427.590.530.698.277 Primary outcome: It is expected to find a greater increase in executive function, verified by the Stroop Test of Colors and Words, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the verification of a statistically significant difference, defined as a P value < 0.05, in the post-exercise values ??between these interventions. ;It is expected to find a greater increase in executive function, verified by the Trail Making Test, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the verification of a statistically significant difference, defined as a P value < 0.05, in the post-exercise values ??between these interventions. Secondary outcome: It is expected to find a greater increase in neurovascular coupling, assessed through transcranial Doppler, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the finding of a statistically significant difference, defined as a value of P < 0.05, in post-exercise values ??between these interventions. ;It is expected to find a greater increase in vasomotor reactivity, assessed through transcranial Doppler, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the finding of a statistically significant difference, defined as a value of P < 0.05, in post-exercise values ??between these interventions. ;It is expected to find a greater increase in cerebral blood flow, assessed by transcranial Doppler, during high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the finding of a statistically significant difference, defined as a P value < 0.05, in the values ??obtained during these interventions.

Conditions reported: Parkinson Disease;C10.228

Registry records for this study

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Study type
Interventional
Interventions
A single group of 18 patients with Parkinson's disease will be submitted to 3 experimental sessions (crossover study) performed in random order: moderate intensity aerobic exercise, high intensity aerobic exercise and control. In all sessions, an intervention period of 30 minutes will be used. In the exercise sessions, patients will exercise on a cycle ergometer. Exercise intensity will correspond to 40-60% of heart rate reserve in the moderate intensity session, and 60-85% of heart rate reserve in the high intensity session. In the control session, patients will remain seated at rest.;G11.427.590.530.698.277
Phases
N/A
Sponsor
Universidade Nove de Julho
Start date reported by registry
2023-01-02 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Raphael Ritti-Dias · +55 019 999406878 · raphaelritti@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Brazil

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.