RESEARCH / PARTICIPATIONBack to the library
← Find a study
Recruiting · registry status

Saliva, chewing and sense of smell

Researchers are collecting saliva and measuring chewing and smell to investigate possible signs of neurological disease.

Learning by observing or collecting information · Study reference: NL-OMON58244

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported date)
2026-05-07

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 to 99 · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: Not reported

Inclusion criteria: Observational group: - Diagnosis PD - Score van = 19 of the MOCA of RUDAS Control group:  - age- and sex matched healthy controls Exclusion criteria: Observational group: - People with atypical forms of parkinsonism, such as Multiple System Atrophy (MSA) and Progressive    Supranuclear Palsy (PSP) - Treated in the past with chemotherapy or radiation therapy in the head and/or neck-region - Diabetes Mellitus or Sjogren’s syndrome Control group:  - Blood relatives with PD - Treated in the past with chemotherapy or radiation therapy in the head and/or neck-region - Diabetes Mellitus or Sjogren’s syndrome
Full study name & original research details

Official study title

Sifting through Spittle: its secretion, characteristics of saliva, and the salivary experience in people with Parkinson’s disease’ - Sifting through Spittle

Short title used by the registry

Sifting through Spittle

Original description

Intervention: Chewing gum: chewing for 60 seconds in order to measure chewing ability. Collect saliva in a cup: 1 x 5 minutes unstimulated and 1x 5 minutes stimulated by chewing on a 5x5cm piece of parafilm.  Sniffin’ Stick Test: to measure olfactory dysfunction. Participants are asked to smell a ‘stick’ which is offered once and identify the scent by choosing from four options. Taste strips: tasting to measure gustatory dysfunction. Participants will be asked to identify the taste and choose between the four tastants and “tasteless” Glass of water: drinking 150ml of water, swallowing as quickly as possible, but stop if difficulties arise. Primary outcome: The primary parameters include subjective salivary experience (xerostomia, salivary loss, and swallowing difficulties) and objective measures of salivary secretion rate (stimulated and unstimulated). Secondary outcome: Secondary parameters comprise unstimulated and stimulated salivary secretion rate, pH and buffered pH of (un)stimulated saliva, spinnbarkeit, mucin5B concentration, amylase concentration, and electrolyte composition.

Conditions reported: Parkinson's, Parkinson's Disease, PD, saliva, xerostomia, hyposialia, hypersialia, sialorrhea, dysphagia Parkinson, Parkinson's disease, saliva, spit, dry mouth, drooling, loss of saliva, swallowing problems;overig;10028037

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Chewing gum: chewing for 60 seconds in order to measure chewing ability. Collect saliva in a cup: 1 x 5 minutes unstimulated and 1x 5 minutes stimulated by chewing on a 5x5cm piece of parafilm.  Sniffin’ Stick Test: to measure olfactory dysfunction. Participants are asked to smell a ‘stick’ which is offered once and identify the scent by choosing from four options. Taste strips: tasting to measure gustatory dysfunction. Participants will be asked to identify the taste and choose between the four tastants and “tasteless” Glass of water: drinking 150ml of water, swallowing as quickly as possible, but stop if difficulties arise.
Phases
NA
Sponsor
Academisch Centrum Tandheelkunde Amsterdam
Start date reported by registry
2026-05-07 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

B.D.M. Dijk · 020 5980412 · b.van.dijk2@acta.nl

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Netherlands

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.