Building a detailed picture of Parkinson's

Inclusion criteria: Prior to enrollment in this clinical investigation, candidates must meet ALL of the following criteria: Patients: • recently diagnosed with PD (N=625; time since Parkinson diagnosis 2 & 65 years) in both patient groups, will be attempted. • 18 years or older; • able to read and speak Dutch • Providing IRB-approved Informed Consent; • Willing, competent and able to comply with all aspects of the protocol, including follow-up schedule and biospecimen collections. Controls: • 18 years or older • Healthy (Self-report) • Is able to read and speak Dutch • Even distribution with respect to gender and age of the patient groups will be attempted • Providing IRB-approved Informed Consent; • Willing, competent and able to comply with all aspects of the protocol, including follow-up schedule and biospecimen collections. Exclusion criteria: Patients • Patients who received brain surgery for Parkinson*s disease, patients who currently use levodopa continuous intestinal gel or patients who are currently receiving apomorphine treatment. • presence of co-morbidities that would hamper interpretation of parkinsonian disability, in the opinion of the lnvestigator. • MoCa score of <=16 (indicates dementia) • Unwillingness to be informed of unexpected medical findings Controls • A history of neurological disorders that affect the brain or central nervous system • Abnormal findings at general neurological examination • Unwillingness to be informed of unexpected medical findings