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A study watch for newly diagnosed Parkinson's

Participants wear a research watch so researchers can follow movement and other body measurements over two years.

Learning by observing or collecting information · Study reference: NL-OMON49224

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported date)
2020-08-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 to 99 · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: Not reported

Inclusion criteria: Prior to enrollment in this clinical investigation, candidates must meet ALL of the following criteria: * Subject has never been treated before with any symptomatic dopaminergic drug treatment for Parkinson*s disease and is not expected to start treatment for motor symptoms of PD within 52 weeks from baseline. * Subject has Parkinson*s disease of <=2 years of duration, defined as the time since the diagnosis was made by a neurologist. * Subject is an adult, at least 18 years of age. * Subject can read and understand Dutch. * Subject has completed the CMO-approved Informed Consent. * Subject is willing, competent, and able to comply with all aspects of the protocol, including follow-up schedule and biospecimen collection. Exclusion criteria: Candidates must be excluded from this study if ANY of the following criteria  are met: * Subject is pregnant or breastfeeding. * Subject has co-morbidities that would hamper interpretation of  parkinsonian disability, such as coincident musculoskeletal abnormalities, in  the opinion of the lnvestigator. * Subject is allergic to nickel.
Full study name & original research details

Official study title

The Personalized Parkinson Project - de novo cohort - PPP NOVO

Short title used by the registry

The Personalized Parkinson Project - de novo cohort

Original description

Intervention: Participants are wearing the Verily study watch during 2 years. Primary outcome: Digitale biomarkers, calculated from the Verily Study Watch data, i.e., . Pulse rate . Skin temperature, Electrodermal activity (sweat) . Movement data (Accelerometer) . Electrocardiogram (ECG) . Altitude, pressure, relative humidity . Environment temperature . Ambient light level . Sound pressure level The development of these digital biomarkers is part of the study. Selection of the digital biomarker is based on it's sensitivity to detect disease progression. Secondary outcome: Clinimetrics (on site, by assessor) - Motor Assessment Subset ON Medication: Hoehn & Yahr stage; UPDRS-Il; UPDRS-Ill (lncluding timed up-and-go tests to assess gait); UPDRS-lV; Freezing of Gait Questionnaire; Standing leg /flamingo Test; Pirouette Test; Pegboard Test; Grip strength. - Neuropsychological Symptoms: UPDRS-I; Montreal Cognitive Assessment; Phonemic Fluency Semantic Fluency; 15 Words Test; Benton Judgment of Line Orientation; Letter Number Sequencing; Symbol Digit Modalities Test. Questionaires: - Neuropsychological symptoms: Beck Depression lnventoryi Quip- RS (impulsivecompulsive disorder); Apathy scale; Trait Anxiety lnventory for Adults; - Other UPDRS-ll;: SCOPA- autonomic; SCOPA- sleep; RBD questionnaire; Epworth sleep questionnaire; SF-12; PDQ-39; Wearing-off questionnaire; Radboud Oral Motor lnventory; Screening Questionnaire on Visual lmpairment; PASE (Physical Activity Scale for the Elderly). Biomarkers * lmaging - ECG: heart rate variability * Biospecimens - Blood: Plasma / PBMCs serum, EDTA plasma (DNA), PAXgene (RNA)

Conditions reported: Parkinson's Disease;10028037

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Participants are wearing the Verily study watch during 2 years.
Phases
NA
Sponsor
Radboud Universitair Medisch Centrum
Start date reported by registry
2020-08-31 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

MJ Meinders · 0243615202 · marjan.meinders@radboudumc.nl

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Netherlands

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.