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Testing ear-based nerve stimulation for circulation control

Researchers study whether gentle stimulation through the ear can affect how the body regulates heart and circulation functions in neurological conditions.

Testing a treatment or activity · Study reference: NCT07557706

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported actual date)
2025-09-15
Main measurements finished (planned)
2026-08-31
Study finished (planned)
2026-12-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 80 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Diagnosis of idiopathic PD * Stable medication for at least 4 weeks prior to the study Exclusion Criteria: * Use of beta blockers * Sustained severe hypertension (\>/= 180/110 mmHg while seated) * Significant uncontrolled cardiac arrhythmia * Unstable angina * Congestive heart failure * History of myocardial infarction * History of seizures * Severe cognitive impairment * Pregnant women or women who are planning to become pregnant
Full study name & original research details

Official study title

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Original description

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

Conditions reported: PARKINSON DISEASE (Disorder)

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
transcutaneous auricular vagus nerve stimulation
Phases
PHASE1
Sponsor
University of Alabama at Birmingham
Start date reported by registry
2025-09-15 (actual)

Registry updated: 2026-06-18 · Status last verified by the registry submitter: 2026-06

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Alexandra Evancho, DPT · 205-975-5221 · amelgin@uab.edu

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Wellness, Health and Research Facility at UAB

Birmingham, Alabama, United States

Recruiting

Alex Evancho · 205-975-5221 · amelgin@uab.edu

Alex Evancho, DPT

Facility not reported

United States

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.