Recruiting · registry status

Understanding reward-seeking and risk-taking

Researchers record brain activity to study how people with Parkinson’s process rewards and make decisions involving risk.

Testing a treatment or activity · Study reference: NCT07409207

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported actual date): 2024-09-01
Main measurements finished (planned): 2029-09-30
Study finished (planned): 2029-09-30

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 40 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center * Planned clinical electrode trajectory that contacts caudate * Age greater than or equal to 40 * Diagnosis of Parkinson's disease or other movement disorder * Able to participate in intraoperative testing * English speaking Exclusion Criteria: * Age less than 40 * Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)

Full study name & original research details

Official study title

Neurophysiology of Reward Signaling in Parkinson's Disease

Original description

The goal of this study is to learn more about the brain activity underlying Parkinson's disease risk taking and reward seeking behaviors. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT07409207 ↗ — RECRUITING; checked 2026-10-11
ClinicalTrials.gov · NCT07409207 ↗ — Recruiting; WHO ICTRP processed 2026-06-22; checked 2026-10-11

Study type: Interventional
Interventions: Neurophysiology recordings; Neural stimulation
Phases: NA
Sponsor: Vanderbilt University Medical Center
Start date reported by registry: 2024-09-01 (actual)

Registry updated: 2026-06-12 · Status last verified by the registry submitter: 2026-02

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Lucas Chang, BA · 615-421-3046 · lucas.m.chang@vumc.org

Sarah Bick, MD · 615-343-9822 · sarah.bick@vumc.org

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Recruiting

Lucas Chang, BA · 615-421-3046 · lucas.m.chang@vumc.org

Sarah Bick, MD

Facility not reported

United States

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.