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Studying an anti-inflammatory medicine in Parkinson’s

Researchers investigate etoricoxib in people with Parkinson’s in relation to inflammation and the condition’s effects.

Testing a treatment or activity · Study reference: NCT07370532

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2026-01-30
Main measurements finished (planned)
2027-11-10
Study finished (planned)
2027-11-20

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 50 years to 70 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Age ≥ 18 years. * Both male and female will be included. * Patients diagnosed with PD according to Unified Parkinson's Disease Rating Scale. Exclusion Criteria: * Breast feeding * Patients with significant liver and kidney function abnormalities. * Alcohol and / or drug abusers. * Patients with known allergy to the study medications * Pregnant women and women with planned pregnancy. * Patients who are currently using other anti-inflammatory drugs.
Full study name & original research details

Official study title

Clinical Study to Evaluate Safety and Efficacy of Etoricoxib in Patients With Parkinson's Disease Treated With Conventional Treatment

Short title used by the registry

Etoricoxib in Patients With Parkinsonian Disease

Original description

Neuroinflammation is considered one of the most important factors contributing critically to pathophysiology of PD . Recently, high mobility group box-1 (HMGB1) protein has been encoded as a potential inflammatory biomarker in PD. HMGB1 mediates immune response mostly through endothelial cells and macrophage activation via targeting two vital cell receptors; Toll-like receptor 4 (TLR4) and advanced glycation end products (RAGE).

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
L-dopa; Etoricoxib
Phases
PHASE2
Sponsor
Ihab Elsayed Hassan
Start date reported by registry
2026-01-30 (actual)

Registry updated: 2026-04-08 · Status last verified by the registry submitter: 2026-04

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

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Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Mansoura University

Al Mansurah, Egypt

Recruiting

Ehab Hassan, PhD · 01067831661 · Ehassan@horus.edu.eg

Facility not reported

Egypt

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.