RESEARCH / PARTICIPATIONBack to the library
← Find a study
Recruiting · registry status

Quality of life during treatment for advancing Parkinson’s

Researchers follow people receiving foslevodopa and foscarbidopa in everyday care, focusing on quality of life earlier in advanced Parkinson’s.

Learning by observing or collecting information · Study reference: NCT07227896

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported actual date)
2026-08-03
Main measurements finished (planned)
2027-10
Study finished (planned)
2027-10

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 80 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Eligibility for Foslevodopa/Foscarbidopa (LDp/CDp) therapy in accordance with approved local label in the participating country and local reimbursement regulations, if applicable * A diagnosis of levodopa-responsive idiopathic Parkinson's Disease (PD) * Adult male or female between 18 and 80 years of age * Disease duration (time since diagnosis) \<10 years * Time since motor fluctuations ≤3 years * H\&Y Stage \<3 in best "on" * "off" time of 2.5-6 hours per day * Naïve to LDp/CDp * Treatment has been optimized with oral/transdermal PD medication in the opinion of the Investigator * Decision to treat with LDp/CDp made by the clinician prior to any decision to approach the participant to participate in the study * Willing and able to comply with procedures required during this study, specifically with entering data and filling questionnaires in an electronic device (tablet). * Prior to any study-related procedures being performed, the participant or Legal Authorized Representative (LAR) must voluntarily sign an Authorization for Use/Disclosure of Data (AUDD)/Informed Consent Form (ICF) according to national regulations once the study has been explained and the participant has the opportunity to have any questions answered Exclusion Criteria: * History of any condition included in the contraindications section of the approved local Foslevodopa/Foscarbidopa (LDp/CDp) label in the participating country * History of treatment with any Device-Aided Therapy (DAT), such as Deep Brain Stimulation (DBS), Continuous Subcutaneous Apomorphine Infusion (CSAI), Levodopa/Carbidopa Intestinal Gel (LCIG)/ Carbidopa/Levodopa Enteral Suspension (CLES), Levodopa/Entacapone/Carbidopa Intestinal Gel (LECIG) * Mini-Mental State Examination (MMSE) score \<24 * Participation in a concurrent investigational or observational clinical trial * Lack of motivation/insufficient language skills to complete the study questionnaires * History of significant skin conditions or disorders (e.g., psoriasis, atopic dermatitis). In case of temporary affections like recent sunburn or open wounds, or in case of permanent affections like acne, scar tissue, tattoo, branding, or colorations, the participant should not be included if the Investigator considers these as interfering with infusion of study drug or study assessments.
Full study name & original research details

Official study title

A Global Real-World Evidence Study on the Effectiveness and Safety/Tolerability of Foslevodopa/Foscarbidopa in Patients Earlier Within Advanced Parkinson's Disease

Short title used by the registry

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease

Original description

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. This study will assess how effective Foslevodopa/Foscarbidopa is in treating adult participants earlier within advanced Parkinson disease under routine clinical practice. Foslevodopa/Foscarbidopa is an approved drug for the treatment of Parkinson's Disease. Approximately 100 adult participants who are prescribed Foslevodopa/Foscarbidopa by their doctors will be enrolled across approximately 40 sites across the world. Participants will receive Foslevodopa/Foscarbidopa subcutaneous infusion as prescribed by their physician. Participants will be followed for up to 6 months. There are no additional examinations due to the study but the participants and caregivers will need to fill several questionnaires to generate data on their motor function and well-being

Conditions reported: Parkinson's Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Not reported
Phases
Not reported
Sponsor
AbbVie
Start date reported by registry
2026-08-03 (actual)

Registry updated: 2026-09-01 · Status last verified by the registry submitter: 2026-08

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Lars Bergmann · +49(0)170 4538568 · lars.bergmann@abbvie.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Texas Movement Disorder Specialists /ID# 278565

Georgetown, Texas, United States

Recruiting

Shaare Zedek Medical Center /ID# 276209

Jerusalem, Jerusalem, Israel

Recruiting

The Chaim Sheba Medical Center /ID# 276210

Ramat Gan, Tel Aviv, Israel

Recruiting

Tel Aviv Sourasky Medical Center /ID# 276212

Tel Aviv, Tel Aviv, Israel

Recruiting

Hadassah Medical Center-Hebrew University /ID# 276211

Jerusalem, Israel

Recruiting

Fundeni Clinical Institute /ID# 277490

Bucharest, Bucharest, Romania

Recruiting

Arcadia Spitale Si Centre Medicale /Id# 277525

Iași, Iaşi, Romania

Recruiting

Neurotim Med /ID# 277500

Timișoara, Timiș County, Romania

Recruiting

Spitalul Clinic Judetean De Urgenta Brasov /ID# 277499

Brasov, Romania

Not yet recruiting

University Hospitals Plymouth NHS Trust /ID# 284977

Plymouth, Devon, United Kingdom

Recruiting

Facility not reported

Australia

Status not reported

Facility not reported

Canada

Status not reported

Facility not reported

Israel

Status not reported

Facility not reported

Croatia

Status not reported

Facility not reported

Netherlands

Status not reported

Facility not reported

Romania

Status not reported

Facility not reported

Spain

Status not reported

Facility not reported

United Kingdom

Status not reported

Facility not reported

United States

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.