RESEARCH / PARTICIPATIONBack to the library
← Find a study
Recruiting · registry status

How does a bent posture affect swallowing and coughing?

Researchers study whether bending forward at the trunk affects the ability to swallow safely and cough in Parkinson’s.

Learning by observing or collecting information · Study reference: NCT06955377

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported actual date)
2025-02-18
Main measurements finished (planned)
2028-02
Study finished (planned)
2029-02

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Diagnosis of Parkinson' s disease * Age ≥ 18 years Exclusion Criteria: * Unreliable performance of MIP, MEP, or grip strength measurements, for example, due to cognitive deficits (assessed by the researcher) * Inadequate lip seal * Significant deformities of the dominant hand that could affect the accuracy of grip strength measurements * Other severe neurological diseases apart from PD * History of unstable cardiovascular disease * Severe pulmonary disease
Full study name & original research details

Official study title

Effect of Forward Trunk Flexion in Patients With Parkinson's Disease on the Airway Defense System

Short title used by the registry

Effect of Trunk Flexion on Airway Defense in Parkinson's Disease

Original description

The main mechanisms of airway protection include a properly functioning swallowing process and a cough. Studies focusing on patients with Parkinson's disease (PD) have previously demonstrated impairments in both swallowing (dysphagia) and coughing (dystussia). Aspiration pneumonia is the leading cause of death in individuals with PD. Swallowing function is directly related to body posture. Postural abnormalities (PA) are a common symptom of PD and significantly contribute to patient disability, affect respiratory function, and reduce quality of life. Previous research has shown that more than 20% of PD patients suffer from some form of PA. Most PD patients with a forward trunk flexion angle greater than 30 degrees report specific difficulties, such as dysphagia. A link has previously been demonstrated between postural abnormalities associated with flexed posture and restrictive ventilatory impairment. It can be assumed that this restrictive ventilatory impairment, which reduces the amount of air the patient can inhale into the lungs and subsequently exhale, negatively affects the strength of voluntary cough. However, this hypothesis has not yet been verified in the mentioned patient group. The primary aim of the study will be to examine the effect of forward trunk flexion (FTF) in Parkinson's disease on the airway defense system.

Further description from the registry

The primary aim of the study will be to verify the potential relationship between forward trunk flexion, respiratory muscle strength, and the strength of voluntary cough. Hypotheses: 1. Forward trunk flexion in patients with Parkinson's disease (PD) will negatively affect respiratory muscle strength and the strength of voluntary cough. 2. Respiratory muscle strength and the strength of voluntary cough will deteriorate more rapidly over a three-year period in patients with PD and forward trunk flexion than in patients with PD without forward trunk flexion. The secondary aim will be to correlate respiratory muscle strength and the strength of voluntary cough with handgrip strength and the pulmonary dysfunction index as potential screening methods. Hypothesis: 1\. Handgrip strength and the pulmonary dysfunction index will correlate with respiratory muscle strength and the strength of voluntary cough.

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Not reported
Phases
Not reported
Sponsor
General University Hospital, Prague
Start date reported by registry
2025-02-18 (actual)

Registry updated: 2025-05-02 · Status last verified by the registry submitter: 2025-04

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Kateřina Dvořáková, MSc. · +420 224 965 513 · katerina.dvorakova@vfn.cz

Martin Srp, PhD. · +420224965513

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

General University Hospital

Prague, Czechia

Recruiting

Kateřina Dvořáková, MSc. · +420 224 965 513 · katerina.dvorakova@vfn.cz

Facility not reported

Czechia

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.