Recruiting · registry status

Testing demanding exercise based on everyday movements

Researchers study high-intensity functional exercise and its effects on physical and thinking abilities in Parkinson’s.

Testing a treatment or activity · Study reference: NCT06879821

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported actual date): 2022-03-14
Main measurements finished (reported actual date): 2022-11-30
Study finished (planned): 2025-04-30

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 40 years to 80 years · Does not accept healthy volunteers

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Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Diagnosis of Parkinson's disease. * Stage I or II (Hoehn - Yahr Scale). * Age between 45 and 80 years. * Independent ambulation for 10 consecutive minutes. * Regular physical exercise. Exclusion Criteria: * Medical contraindication for physical activity, deafness or limited hearing and very low vision or blind. * Vestibular disorders that compromise balance. * Psychotic or severe cognitive disorder. * Decompensation or changes in medication. * Surgical intervention in the last 6 months. * Sedentary persons

Full study name & original research details

Official study title

Effectiveness of a High-intensity Functional Training (HIFT) Program on Functional and Cognitive Performance in People with Parkinson's Disease.

Short title used by the registry

High-intensity Functional Training on Functional and Cognitive Performance in People with Parkinson's Disease.

Original description

Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.

Further description from the registry

The hypothesis is that high-intensity functional training (HIFT), at a motor and cognitive level, provides a greater benefit than conventional programs of strength, balance and cognition, on the functionality and cognitive capacity of people with Parkinson's disease. Overall objective: \- To assess whether the HIFT training program is associated with significant improvements in functional and cognitive capacity compared to conventional strength, balance and cognition programs in Parkinson's patients. Secondary objectives: 1. To assess whether the HIFT program improves the quality of life in patients with PD. 2. To study whether the HIFT program reduces the degree of dependency of patients with PD. 3. To determine if the HIFT program improves physical performance in patients with PD 4. To assess whether the HIFT program reduces the risk of falls in patients with PD. 5. To investigate whether the HIFT program improves balance in patients with PD. 6. To determine if the HIFT program improves functional capacity in patients with PD. 7. To study whether the HIFT program improves cognitive function in patients with PD

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT06879821 ↗ — RECRUITING; checked 2026-10-13
ClinicalTrials.gov · NCT06879821 ↗ — Recruiting; WHO ICTRP processed 2025-03-24; checked 2026-10-13

Study type: Interventional
Interventions: high intensity functional training
Phases: NA
Sponsor: Fundacion Para La Investigacion Hospital La Fe
Start date reported by registry: 2022-03-14 (actual)

Registry updated: 2025-03-17 · Status last verified by the registry submitter: 2025-02

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Marta Aguilar Rodríguez, PHD · +34-963983855 · marta.aguilar@uv.es

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

University of Valencia

Valencia, Valencia, Spain

Recruiting

Marta Aguilar Rodríguez · 963 98 38 55 · marta.aguilar@uv.es

Ismael Vargas Villanueva · 620007093 · ismaelvargasvillanueva@gmail.com

Facility not reported

Spain

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.