Recruiting · registry status

Mindfulness practice for people with Parkinson’s and their caregivers

Researchers study a mindfulness programme done by people with Parkinson’s together with their caregivers, looking at several aspects of wellbeing.

Testing a treatment or activity · Study reference: NCT06821230

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported actual date): 2025-02-11
Main measurements finished (planned): 2027-06-30
Study finished (planned): 2027-06-30

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria of PwPD: * Chinese patients with idiopathic mild-moderate PD (as indicated by the Hoehn and Yahr Scale stages I-III: those with unilateral/bilateral symptoms, with/without postural instability who are able to walk/stand unassisted) * Aged ≥18 years Inclusion Criteria of caregivers of PwPD: \- Self-identified as the primary caregivers of their patient Either patient or caregiver needs to experience at least mild negative emotions (as indicated by the 21-item Depression, Anxiety and Stress Scale \[DASS21\] score of Depression subscale ≥10, Anxiety subscale ≥8, or Stress subscale ≥15) Both need to be able to communicate in Cantonese and provide written consent. Exclusion Criteria: * Engage in regular supervised mind-body practices such as Tai Chi, yoga, or other forms of mindfulness training (\>2 times per week) * Have a pre-existing acute psychotic disease * Currently participating in any other behavioral or pharmacological trial * Have significant cognitive impairment, as indicated by an Abbreviated Mental Test score≤ 6 * Have other contraindications that may limit their full participation (e.g., severe hearing/vision impairment)

Full study name & original research details

Official study title

Enhancing Psychological Wellbeing and the Patient-caregiver Relationship Through Dyadic Mindfulness: A Randomized Controlled Trial in People With Parkinson's Disease and Their Caregivers

Short title used by the registry

Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers

Original description

The proposed two-arm randomized waitlist-controlled trial will use a mixed-methods design to investigate the effects of dyadic mindfulness on physio-psycho-spiritual outcomes in people with Parkinson's Disease (PwPD) and their family caregivers. One hundred Chinese patient-caregiver dyads will be randomized to receive eight weekly 90-minute dyadic mindfulness sessions or usual care. Outcome measures include negative emotions (primary outcome), patient-caregiver relationship, mindfulness, HRQOL, gut microbiome, PD-related symptoms, and caregiving burden. An actor-partner interdependence model will be used to explore the interactions of treatment effects within the dyads. The dyads will be assessed at baseline(T0), post-intervention(T1), and 4-months post-intervention(T2). The investigators will also invite 25 dyads to attend in-depth interviews exploring their experiences, perceived changes, and factors attributable to the effectiveness/ineffectiveness of the intervention. Generalized linear mixed-effects (GLME) with intention-to-treat analysis will be used to compare the changes in outcomes over time within and between the two arms. The findings will be triangulated to provide a comprehensive evaluation of the intervention's effectiveness. This study will generate rigorous scientific evidence to inform the application of dyadic mindfulness as a public health practice preventing the progression of psychological distress in PwPD and caregivers to clinically severe levels. Its self-help nature also enriches the primary care for this clinical cohort.

Conditions reported: Mindfulness; Caregivers; Movement Disorders; Neurodegenerative Disease; Dyadic Intervention; Psychosocial Health; Parkinsons Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT06821230 ↗ — RECRUITING; checked 2026-10-11

Study type: Interventional
Interventions: Dyadic mindfulness
Phases: NA
Sponsor: The University of Hong Kong
Start date reported by registry: 2025-02-11 (actual)

Registry updated: 2026-06-01 · Status last verified by the registry submitter: 2026-05

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Jojo Yan Yan Kwok · 852 39176644 · jojoyyk@hku.hk

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

School of Nursing, The University of Hong Kong

Hong Kong, Hong Kong

Recruiting

Jojo Yan Yan Kwok · +852 39176644 · jojoyyk@hku.hk

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.