Recruiting · registry status

Music in everyday life with Parkinson’s or Alzheimer’s

Researchers compare musical activities and thinking abilities in older adults with Parkinson’s or Alzheimer’s disease.

Testing a treatment or activity · Study reference: NCT06688968

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date): 2025-02-04
Main measurements finished (planned): 2025-12-01
Study finished (planned): 2025-12-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 60 years and over · Also accepts healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: General inclusion criteria: * 60 years and older * French-speaking and volunteering for the study * Living at home with a relative Alzheimer's disease inclusion criteria: * Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984) * MMSE greater than or equal to 20 Inclusion criteria Parkinson's disease : * Diagnosis of Idiopathic Parkinson's disease * MMSE greater than or equal to 20 Exclusion Criteria: * No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes) * Autistic disorders * History of stroke or head trauma * Unstable medical condition (cancer) * Subject unable to read and/or write * Hearing impairment without hearing aids * Refusal of consent after information * Persons unable to give consent, research carried out in emergency situations, etc.) * Non-affiliation with a social security scheme * Person deprived of liberty (by judicial or administrative decision, or forced hospitalization) * Person under legal protection (guardianship, curatorship, legal protection) * Person participating in another research project with an exclusion period still in progress

Full study name & original research details

Official study title

Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment

Short title used by the registry

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Original description

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects. The main questions it aims to answer are: 1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects. 2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up. Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including : * A semi-structured interview to check the participants eligibility and gather demographic data. * Neuropsychological tests and questionnaires will then be administered. * A relative of the study participant will help complete questionnaires.

Further description from the registry

Music therapy appears to be highly relevant as a Non-Medication Intervention in Alzheimer s (AD) and Parkinson s disease (PD). It is said to reduce depressive symptoms following music therapy sessions in dementia . With regard to Parkinson s disease, music therapy brings benefits in terms of motor skills, communication, breathing and emotional aspects. Reviews point to the need to differentiate beneficial effects according to different pathologies. To date, no study has investigated the evolution of sensitivity to musical reward in AD. Furthermore, no study has discriminated the evolution of musical engagement in several neurodegenerative pathologies.

Conditions reported: Alzheimer Disease, Early Onset; Parkinsons Disease with Dementia; Non Pharmacological Intervention

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT06688968 ↗ — RECRUITING; checked 2026-10-13

Study type: Interventional
Interventions: neuropsychologist interview; questionnaire
Phases: NA
Sponsor: University Hospital, Montpellier
Start date reported by registry: 2025-02-04 (actual)

Registry updated: 2025-03-19 · Status last verified by the registry submitter: 2025-03

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Mikaël Genguelou, PhD · 06.04.45.37.94. · mikael.genguelou@univ-montp3.fr

KARIM BENNYS, MD · 04.67.33.72.32 · k-bennys@chu-montpellier.fr

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Montpellier Seniors' Association

Montpellier, Hérault, France

Not yet recruiting

Mikaël Guenguelou, PhD · 06.04.45.37.94. · mikael.genguelou@univ-montp3.fr

CHU de Montpellier - CEPMo

Montpellier, Hérault, France

Recruiting

Mahmoud CHARIF, MD · 0467337413 · m-charif@chu-montpellier.fr

CHU de Montpellier - CMRR

Montpellier, Hérault, France

Not yet recruiting

Karim BENNYS, MD · 04.67.33.60.29 · k-bennys@chu-montpellier.fr

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.