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Testing spinal stimulation for freezing while walking

Researchers study stimulation near the upper-back part of the spinal cord in people with advanced Parkinson’s and walking freezes.

Testing a treatment or activity · Study reference: NCT06630702

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported actual date)
2024-09-20
Main measurements finished (planned)
2027-12-31
Study finished (planned)
2027-12-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

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Who can join?

Ages 40 years to 85 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Age:40-85 years old. * Patients with primary Parkinson\'s disease who have been diagnosed by a movement disorder specialist for more than 5 years. Although they have a clear response to drugs, they have a frozen gait that cannot be controlled by drugs. Lower limb pain may be present with or without Parkinson\'s non-motor symptoms. * No other secondary gait problems. Exclusion Criteria: * Atypical Parkinson's disease. * Patients with spinal cord injuries. * Medication-controlled frozen gait. * It is expected that there are lesions near the implantation area causing spinal canal stenosis or myelopathy (can be ruled out by MRI). * It is expected that the implantation area has undergone previous surgery or there is infection near the implantation area, which may affect the success rate of implantation or increase concerns about complications (such as severe extraspinal adhesion, or spinal cord damage in previous surgeries). * People with abnormal coagulation function (such as hemophilia patients) or those who have been controlled by long-term use of antithrombotic drugs and cannot stop taking them in a short period of time. * CDR (Clinical Dementia Rating Scale) ≧2. 8. Those who are allergic to developer.
Full study name & original research details

Official study title

Application of Thoracic Epidural Spinal Cord Stimulation (SCS) for Managing Freezing of Gait (FOG) in Patients With Advanced Parkinson's Disease

Short title used by the registry

Application of Thoracic Epidural SCS for Managing FOG in Patients With Advanced Parkinson's Disease

Original description

Spinal cord stimulation (SCS) has proven to be effective for pain that is unresponsive to medication. This technique involves an anesthesiologist or a neurosurgeon placing stimulation electrodes at the thoracic vertebrae to provide pain relief. Although SCS is not currently a standard treatment for patients with Parkinson's disease, recent studies have shown that Parkinson's patients who experience intolerable pain and undergo SCS treatment not only experience pain relief but also show improvements in gait and other Parkinson's symptoms. Therefore, the investigators aim to use temporary, minimally invasive SCS electrodes to help patients with nrFOG (non-responsive Freezing of Gait) improve their stability and reduce their risk of falls.

Conditions reported: Parkinson Disease; Freezing of Gait; Spinal Cord Stimulation

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
SCS electrode stimulation 1; SCS electrode stimulation 2; SCS electrode stimulation 3
Phases
NA
Sponsor
National Taiwan University Hospital
Start date reported by registry
2024-09-20 (actual)

Registry updated: 2025-11-20 · Status last verified by the registry submitter: 2025-11

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Kai-Hsiang Chen, M.D. · +886-3-5326151 · stanleychen1230@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

National Taiwan University Hospital Hsin-Chu Branch

Hsinchu, Hsinchu City, Taiwan

Recruiting

Kai-Hsiang Chen, M.D. · +886-3-5326151 · stanleychen1230@gmail.com

Facility not reported

Taiwan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.