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Following people who act out dreams for signs of Parkinson’s

Researchers combine clinical assessments, imaging and computer analysis to study Parkinson’s risk in people with REM sleep behaviour disorder, which involves acting out dreams.

Testing a treatment or activity · Study reference: NCT06629207

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2024-10-07
Main measurements finished (planned)
2026-08-01
Study finished (planned)
2026-08-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: 1. Confirmed clinical iRBD diagnosis by movement disorder specialists according to the International Classification of Sleep Disorders 2. Written informed consent Exclusion Criteria: 1. Known diagnosis of PD or other neurodegenerative disorder 2. Unequivocal signs of parkinsonism on examination 3. Narcolepsy or other known causes of RBD 4. Moderate to severe obstructive sleep apnea 5. Abnormal neurological or MRI examination
Full study name & original research details

Official study title

Artificial Intelligence on Molecular Imaging to Predict the Risks of Parkinson's Disease for Patients With Rapid Eye Movement Sleep Behavior Disorder

Short title used by the registry

Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder

Original description

The study aims to systematically document the course of REM sleep behavior disorder (RBD) and investigate possible clinical and imaging biomarkers for disease progression and conversion risk to Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). The study will use artificial intelligence to analyze imaging and develop a reliable method to predict and stratify patients approaching conversion to overt a-synucleinopathy. Participants will be clinically evaluated and 2 imaging procedures will be done.

Conditions reported: Parkinson Disease; REM Sleep Behavior Disorder; Dementia, Lewy Body

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
PET/CT with 18-FDG; SPECT : 123 I-FP-CIT (DATSCAN); MRI
Phases
NA
Sponsor
Insel Gruppe AG, University Hospital Bern
Start date reported by registry
2024-10-07 (actual)

Registry updated: 2024-11-08 · Status last verified by the registry submitter: 2024-11

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Axel Rominger, Prof. Dr. med. · +41 316322610 · axel.rominger@insel.ch

Franziska Strunz, PhD · +41 316643022 · studies.nuk@insel.ch

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Inselspital, University Clinic for Nuclear Medicine

Bern, Switzerland

Recruiting

Axel Rominger, Prof. Dr. med. · +41 31 632 26 10 · axel.rominger@insel.ch

Franziska Strunz, PhD · +41 31 66 4 30 22 · studies.nuk@insel.ch

Facility not reported

Switzerland

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.