Recruiting · registry status

Training balance before taking the first step

Researchers study training aimed at the body adjustments needed to start walking in Parkinson’s.

Testing a treatment or activity · Study reference: NCT06598891

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported actual date): 2024-10-09
Main measurements finished (planned): 2026-05
Study finished (planned): 2026-05

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 20 years and over · Does not accept healthy volunteers

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Sex eligibility reported by registry: all

Inclusion Criteria: \- Clinical diagnosis of Parkinson disease. Exclusion Criteria: * Musculoskeletal injuries on legs * Osteoporosis. * Any peripheral or central nervous system injury or disease patients.

Full study name & original research details

Official study title

Effect of Combined PAS Balance Training on Individuals With PD

Short title used by the registry

PAS Balance Training for Parkinson Disease (PD)

Original description

Gait initiation (GI) difficulty is a common problem in individuals with Parkinson's disease (PD), often linked to impaired anticipatory postural adjustments (APA). Currently, there are no targeted rehabilitation programs designed specifically for GI-related APA in PD patients. Research has shown that while motor learning deficits are common in PD, explicit learning is better preserved than implicit learning. Therefore, a GI-related APA training system using an explicit learning model could be particularly effective for this population. During motor learning, long-term potentiation (LTP) increases the excitability of the primary motor cortex. Paired associative stimulation (PAS) has been demonstrated to induce LTP-like changes in the motor cortex, making it a potential priming method to enhance motor learning. However, the priming effect of PAS targeted at leg muscles and the motor cortex on motor learning related to GI-APA has not been previously studied. The objectives of this study are: 1. To investigate the effects of explicit and implicit training on GI-related APA. 2. To evaluate the priming effect of PAS on GI-related APA training and the associated plasticity changes in the motor cortex.

Conditions reported: PD - Parkinson's Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT06598891 ↗ — RECRUITING; checked 2026-10-13
ClinicalTrials.gov · NCT06598891 ↗ — Recruiting; WHO ICTRP processed 2024-10-21; checked 2026-10-13

Study type: Interventional
Interventions: Weight shift training and APA feedback; Paired associative stimulation
Phases: NA
Sponsor: Chang Gung University
Start date reported by registry: 2024-10-09 (actual)

Registry updated: 2024-10-10 · Status last verified by the registry submitter: 2024-10

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

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Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Chang Gung University

Taoyuan, Taiwan

Recruiting

Ya-Ju Chang, PhD · 88632118800 · yjchang@mail.cgu.edu.tw

Facility not reported

Taiwan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.