RESEARCH / PARTICIPATIONBack to the library
← Find a study
Recruiting · registry status

Studying brain activity patterns during movement

Researchers investigate how patterns of electrical activity across connected brain regions relate to movement symptoms in Parkinson’s.

Testing a treatment or activity · Study reference: NCT06438419

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported actual date)
2025-04-16
Main measurements finished (planned)
2027-04
Study finished (planned)
2027-04

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 75 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Male or Female * 18 to 75 years-old * With idiopathic Parkinson's disease * Having a STN-DBS with a PERCEPT™ for less than a year or being candidate for STN-DBS with the PERCEPT™ device (first-implantation) * Able to perform the simple motor task * Patients covered by a health insurance scheme * Giving free, informed, written consent signed by the participant and the investigator. Exclusion Criteria: * Be incapable of giving consent personally. * Be subject to a legal protection measure (curatorship, guardianship) or be placed under judicial protection. * Being pregnant or breastfeeding * Present a serious and/or decompensated somatic or psychiatric illness.
Full study name & original research details

Official study title

Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range

Original description

Expression of hypokinetic and hyperkinetic motor symptoms in Parkinson's disease (PD) is associated with pathological synchronous oscillations of neuronal activity (local field potential/LFP) in the cortico-subcortical network with a wide frequency range. In the present project, we propose to study cortico-subcortical oscillations and their synchronization in patients operated for PD (subthalamic deep brain stimulation (STN-DBS)) during distinct pharmacological and stimulation conditions (hypokinetic and hyperkinetic), using a simple motor task.

Further description from the registry

To define the link between the characteristics of neuronal oscillations (frequency, amplitude, phase relationship) within the cortico-subcortical network and the movement, we designed a simple motor task of gripping/pulling a lever. The LFPs will be collected at the cortical and subcortical levels (STN) during the motor task using a high-resolution EEG (HR-EEG) and the Percept™ system (Medtronic). Recordings will be realized in four conditions: without pharmacological treatment and without stimulation (Off condition), without pharmacological treatment and during stimulation (DBS condition), during pharmacological treatment and without stimulation (DOPA condition) and during pharmacological treatment and stimulation (DOPA+DBS condition).

Conditions reported: Parkinson Disease; Hyperkinesis; Hypokinesia

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Electrophysiological recordings
Phases
NA
Sponsor
University Hospital, Bordeaux
Start date reported by registry
2025-04-16 (actual)

Registry updated: 2025-05-02 · Status last verified by the registry submitter: 2025-04

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

GUEHL Dominique, Pr · 5 57 82 12 42 · dominique.guehl@chu-bordeaux.fr

Claire BRANDET · claire.brandet@chu-bordeaux.fr

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Bordeaux University Hospital

Bordeaux, France

Recruiting

Dominique Guehl, Pr · dominique.guehl@chu-bordeaux.fr

Claire BRANDET · claire.brandet@chu-bordeaux.fr

Facility not reported

France

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.