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Testing tenofovir for early Parkinson’s

Researchers investigate the safety and effects of tenofovir disoproxil fumarate on movement symptoms in early Parkinson’s.

Testing a treatment or activity · Study reference: NCT06356662

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2024-01-23
Main measurements finished (planned)
2025-12-31
Study finished (planned)
2025-12-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 65 years · Does not accept healthy volunteers

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Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * 1: Parkinson's disease: Hoehn Yahr= 1 to 2.5 2: MMSE score≥24 Exclusion Criteria: * 1: essential tremor, stroke, epilepsy and other well-defined neurological disorders 2: Or have received deep brain stimulation and other brain surgery 3: Abnormal liver and kidney function 4: Infected with chronic hepatitis B or AIDS (HIV-1 infection) 5: Severe depression, schizophrenia, other psychiatric disorders or drug dependence 6: Other serious physical diseases such as heart, lung, liver, kidney disease, blood disease and malignant tumor 7: Pregnant or lactating women and seniors over 65 years of age 8: Allergy or other contraindications to the investigational drug
Full study name & original research details

Official study title

Efficacy and Safety of Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease

Short title used by the registry

Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease

Original description

To evaluate the efficacy and safety of tenofovir disoproxil fumarate in the treatment of Parkinson's disease. The changes of motor symptoms and the occurrence of adverse reactions in early Parkinson's disease patients who took tenofovir disoproxil fumarate and did not take Tenofovir disoproxil fumarate at different time points were compared.

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Tenofovir Disoproxil Fumarate
Phases
PHASE1
Sponsor
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Start date reported by registry
2024-01-23 (actual)

Registry updated: 2025-02-17 · Status last verified by the registry submitter: 2025-02

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

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Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

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Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Guohua Zhao

Hangzhou, Zhejiang, China

Recruiting

Zhao Guohua, Doctor · +86 13777812308 · gzhao@zju.edu.cn

Facility not reported

China

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.