RESEARCH / PARTICIPATIONBack to the library
← Find a study
Recruiting · registry status

How do genes relate to thinking and behaviour?

Researchers investigate how genetic differences in Parkinson’s relate to thinking abilities and behaviour.

Learning by observing or collecting information · Study reference: NCT06329739

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported actual date)
2021-12-14
Main measurements finished (planned)
2031-12-14
Study finished (planned)
2031-12-14

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * diagnosed with Parkinson's Disease (PD) * in use of dopaminergic medication (L-Dopa and/or dopamine agonists) * genetic testing for mendelian forms of PD * able to provide informed consent to participate in the study Exclusion Criteria: * Patients underwent Deep Brain Stimulation (DBS) treatment
Full study name & original research details

Official study title

Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes in Patients Undergoing Dopaminergic Treatment

Short title used by the registry

Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes

Original description

The genetic landscape of Parkinson's disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. This knowledge has the potential to have a major impact in the clinical care of people with PD. The goal of this observational study is to evaluate the impact of genetic mutation on behavior and cognition in PD patients. Patients will be assessed over time using test, questionnaire and standardised clinica scales. An initial assessment and annual follow-up assessments will be carried out for 5 years. Researchers will compare data collected from patients with genetic mutation versus patients without mutation.

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Clinical examinations and clinical scales administration
Phases
Not reported
Sponsor
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Start date reported by registry
2021-12-14 (actual)

Registry updated: 2024-03-26 · Status last verified by the registry submitter: 2024-03

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Francesca Mameli, Dr · 0255033621 · francesca.mameli@policlinico.mi.it

Fabiana Ruggiero, Dr · 0255033621 · fabiana.ruggiero@policlinico.mi.it

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

Recruiting

Francesca Mameli · 0255033621 · francesca.mameli@policlinico.mi.it

Facility not reported

Italy

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.