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Testing acupuncture in Parkinson’s with ongoing appendix inflammation

Researchers investigate acupuncture in people who have Parkinson’s and chronic appendicitis, or ongoing inflammation of the appendix.

Testing a treatment or activity · Study reference: NCT06304285

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (planned)
2024-03-01
Main measurements finished (planned)
2026-12-31
Study finished (planned)
2026-12-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

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Who can join?

Ages 40 years to 70 years · Does not accept healthy volunteers

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Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Patients presenting with bradykinesia, combined with resting tremor and/or myotonia. * Appendix CT suggested chronic appendicitis evaluated by two experienced experts. * All subjects and their guardians give informed consent to the content of this study and sign informed consent. * Normal coagulation function. * If the patient had taken oral anti-PD drugs, it had been stable for at least 2 weeks at enrollment. Exclusion Criteria: * Treatment with dopamine blockers or dopamine depleters in doses and time courses consistent with drug-induced parkinsonism. * Neuroimaging examination of presynaptic dopaminergic system function was normal. * Patients who had suffered severe brain trauma or underwent complex craniotomy within 5 years prior to enrollment. * Cognitive disorders that are not on the Parkinson's spectrum, such as Alzheimer's disease, frontotemporal dementia, and Niemann-Pick disease, have been diagnosed. * People diagnosed with severe neuropsychiatric disorders (epilepsy, bipolar disorder, major depressive episode, etc.) according to DSM-V. * Complicated with serious systemic diseases, disorders of consciousness, stroke, serious coronary heart disease, diabetes, liver and kidney diseases, and serious visual and hearing disorders. * Patients with severe organic or functional dysphagia;Those who were deemed by the researcher to be unable to complete the visit and auxiliary examination as required by the study protocol.
Full study name & original research details

Official study title

A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis: a Single-center, Randomized, Double-blind Study

Short title used by the registry

A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis

Original description

The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients. Recent studies have found that these PD symptoms are closely related to the intestine. For several cases of PD syndrome patients complicated with chronic appendicitis, our research group conducted acupuncture on points related to constipation and chronic appendicitis, and found that constipation and related motor symptoms of patients could be significantly improved. Clinical studies have shown that acupuncture also has a certain therapeutic effect on non-motor symptoms of Parkinson's disease, such as anxiety and depression, decreased olfactory function, sleep disorders, constipation, early skeletal muscle pain, cognitive dysfunction, etc., which can delay the progression of the disease and improve the quality of life of patients. Starting from intestinal acupuncture, this project further clarified the role of acupuncture treatment in the comprehensive treatment of PD

Conditions reported: Parkinson's Disease; Chronic Appendicitis; Acupuncture

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Acupuncture treatment; Sham acupuncture treatment
Phases
NA
Sponsor
The First Affiliated Hospital of University of Science and Technology of China
Start date reported by registry
2024-03-01 (estimated)

Registry updated: 2024-03-12 · Status last verified by the registry submitter: 2024-03

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Yuhua Chen, M.M.S. · +8615955236270 · yh1215@mail.ustc.edu.cn

Chao Han, M.D. · +8615255629713 · 15255629713@193.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

The First Affiliated Hospital of University of Science and Technology of China

Hefei, Anhui, China

Recruiting

Yuhua Chen, M.M.S. · +8615955236270 · yh1215@mail.ustc.edu.cn

Chao Han, M.D. · +8615255629713 · chaohan@ustc.edu.cn

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.