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Measuring how exercise affects brain signals

Researchers use an implanted brain stimulation device to measure brain signals during exercise in people with Parkinson’s.

Learning by observing or collecting information · Study reference: NCT06296810

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2024-09-01
Main measurements finished (planned)
2025-12
Study finished (planned)
2025-12

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 20 years to 70 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: Persons with PD who have a Medtronic DBS Sensight implant and a Percept IPG. \- Exclusion Criteria: Persons not meeting the above listed implant criteria Persons not meeting the age limit criteria Persons who are not able to complete the study exercise Persons not able to comprehend and consent to study participation.
Full study name & original research details

Official study title

Implementation of Adaptive DBS to Offset STN Dysregulation During Exercise and Reduce Exertion in Parkinson's Disease

Short title used by the registry

Adaptive DBS to Offset STN Dysregulation During Exercise in PD

Original description

The investigators conduct a prospective study to evaluate the effects of exercise on Parkinson's Disease brain biomarkers detected with the PerceptTM PC neurostimulator.

Further description from the registry

The investigators will conduct a prospective study to evaluate the effects of exercise on Local Field Potential biomarkers detected from the subthalmic nuclues in Parkinson's Disease with the PerceptTM PC neurostimulator. Subsequently, adaptive Deep Brain Stimulation applied in response to low beta peak (L-beta; 13-20Hz) will be performed to evaluate feasibility of whether aDBS can offset the effects of exacerbation of parkinsonism during exercise performance and recovery.

Conditions reported: Parkinson Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
aDBS
Phases
Not reported
Sponsor
University of Colorado, Denver
Start date reported by registry
2024-09-01 (actual)

Registry updated: 2025-03-17 · Status last verified by the registry submitter: 2025-03

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Pamela David Gerecht, PhD · 303-724-4134 · pamela.davidgerecht@cuanschutz.edu

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

University of Colorado

Aurora, Colorado, United States

Recruiting

Pamela David Gerecht, PhD · 303-724-4134 · pamela.davidgerecht@cuanschutz.edu

Drew Kern, MD

Facility not reported

United States

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.