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Studying brain rhythms involved in movement

Researchers investigate patterns of activity in brain regions involved in movement, including how these patterns change with movement conditions.

Testing a treatment or activity · Study reference: NCT06241924

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2024-02-05
Main measurements finished (planned)
2027-02-05
Study finished (planned)
2027-02-05

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 75 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion criteria : * Male or Female * Between 18 and 75 years of age * With Parkinson's disease and already operated with implantation of electrodes in the Subthalamic nucleus connected to a PERCEPT (TM) device. * Giving free, informed, written consent signed by the participant and the investigator Or * With drug-resistant epilepsy and benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG * With at least one electrode exploring the basal ganglia or the thalamus. * Able to perform the simple motor task * Affiliated or beneficiary of a social security scheme; * Giving free, informed, written consent signed by the participant and the investigator Exclusion criteria: * Be incapable of giving consent personally * Be subject to a legal protection measure or be placed under judicial protection; * Being pregnant or breastfeeding * Present a serious and/or decompensated somatic or psychiatric illness
Full study name & original research details

Official study title

Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement

Original description

The expression of hypokinetic and hyperkinetic motor symptoms is accompanied by pathological synchronous oscillations of neuronal activity in this cortico-subcortical network with a wide frequency range. The purpose of this research is to study cortico-subcortical oscillations and their synchronization in two pathologies emblematic of hypokinetic (Parkinson's disease) and hyperkinetic (epilepsies) phenomena using a simple motor task and comparing different situations.

Further description from the registry

In order to define the link between the characteristics of the oscillations (frequency, amplitude, phase relation) within this cortico-subcortical network and movement (normal or pathological) in humans, a simple motor task of gripping/pulling a lever has been designed. The local field potentials (LFPs) will be collected during the same motor task in : i) patients with Parkinson's disease, using a high-resolution electroencephalogram (EEG) and the PERCEPT(TM) system (Medtronic) equipped with a "sensing" function for deep LFP recordings and in EEG-HR (for high resolution) for cortical recordings ii) patients with focal drug-resistant epilepsy, during a pre-surgical assessment by stereo-electro-encephalography (SEEG). The SEEG allows the recording of both the cortex and the subcortical regions in a concomitant manner, and a direct correlation can be studied.

Conditions reported: Parkinson Disease; Epilepsy

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
High Resolution Electroencephalogram (EEG-HR); Stereo-electro-encephalography (SEEG)
Phases
NA
Sponsor
University Hospital, Bordeaux
Start date reported by registry
2024-02-05 (actual)

Registry updated: 2025-07-23 · Status last verified by the registry submitter: 2025-07

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Jérôme AUPY, Docteur · 05 56 71 43 33 · jerome.aupy@u-bordeaux.fr

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

CHU de Bordeaux

Bordeaux, France

Recruiting

Jérôme Aupy · 05 56 71 43 33

Olivier Branchard · 05 57 82 06 97 · olivier.branchard@chu-bordeaux.fr

Facility not reported

France

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.