Recruiting · registry status

How electrode location affects movement symptoms

Researchers study beneficial and unwanted movement effects of stimulating different locations in a deep brain area in Parkinson’s.

Testing a treatment or activity · Study reference: NCT05557864

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date): 2016-08-25
Main measurements finished (planned): 2026-12-31
Study finished (planned): 2026-12-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 21 years to 89 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * diagnosis of idiopathic PD * have undergone neurosurgery to implant deep brain stimulators in the globus pallidus (GP DBS) or subthalamic nucleus (STN) * Existing 7T brain imagery Exclusion Criteria: * history of musculoskeletal disorders that significantly affect movement of the upper or lower limbs * other significant neurological disorder * history of dementia or cognitive impairment as found with UBACC (or MacCAT-CR) * post-operative complications or adverse effects

Full study name & original research details

Official study title

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease; Udall Project 2 Aims 1 & 2

Short title used by the registry

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

Original description

This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant to dopamine replacement therapy, these experiments will likely have major impact on clinical practice by providing a potential strategy to these medically intractable symptoms.

Conditions reported: Parkinson's Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT05557864 ↗ — RECRUITING; checked 2026-10-13

Study type: Interventional
Interventions: Deep Brain Stimulation
Phases: NA
Sponsor: University of Minnesota
Start date reported by registry: 2016-08-25 (actual)

Registry updated: 2026-01-26 · Status last verified by the registry submitter: 2026-01

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Colum MacKinnon, PhD · cmackinn@umn.edu

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

University Of Minnesota

Minneapolis, Minnesota, United States

Recruiting

Colum MacKinnon, PhD · cmackinn@umn.edu

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.