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Can hands-on treatment of the spine affect breathing?

Researchers test whether physiotherapy techniques that move the spine affect breathing in people with Parkinson’s.

Testing a treatment or activity · Study reference: NCT04941326

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2021-08-15
Main measurements finished (planned)
2025-12-01
Study finished (planned)
2025-12-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 50 years to 85 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Have been diagnosed with Parkinson's disease * Volunteering to participate in the study * Modified Medical Research Council (MMRC) score \>2 Exclusion Criteria: * Those with COVID-19 * Diseases that increase intra-abdominal pressure * Diseases affecting diaphragmatic motility * Those who had a recent thoracic or abdominal operation * Those who have a parenchymal, pleural or chest wall mass that will cause restriction on a recent chest X-ray or CT will not be included in the study
Full study name & original research details

Official study title

Investigation of the Effect of Spinal Mobilization and Respiration Techniques on Posture and Respiratory Function in Parkinson's Patients

Short title used by the registry

The Effect of Spinal Mobilization on Respiratory Parameters in Parkinson's Disease Patients

Original description

Parkinson's patients suffer from respiratory distress for different reasons. It is thought that physiotherapy methods that have an indirect effect on the diaphragm can improve respiratory functions. The aim of this study is to investigate the effects of spinal mobilization and diaphragmatic breathing techniques on respiratory function.

Further description from the registry

Respiratory complications are one of the most common causes of death in Parkinson's patients. Camptocormia may develop in Parkinson's disease and other pathological conditions involving the basal ganglia, which can be defined as an abnormal flexion of the thoracolumbar spine of 45° or more, which increases during walking or standing and disappears completely in the supine position. Parkinson's patients with camptocormia often complain of dyspnea, which can be attributed to reduced lung capacity due to limited chest expansion. Restrictive changes due to respiratory muscle dysfunction in Parkinson's disease, upper airway obstruction, abnormal ventilatory control, and drug use such as levodopa have an effect on respiratory functions. Restrictive dysfunction has been reported in 28-94% of patients with Parkinson's. Postural disorders such as camptocormia can also lead to restriction. One study found that the lung volumes of Parkinson's disease patients with camptocormia decreased, although it was not associated with major clinical changes. Diaphragmatic dyskinesia in Parkinson's patients may also lead to a restrictive deterioration in respiratory functions. Studies examining the effects of chest and diaphragm mobilization on spirometric parameters in patients with cerebral palsy reported that the applied mobilization and soft tissue techniques improved FEV1 and FVC. The effect of indirect diaphragmatic treatments with vertebral mobilization in individuals with Parkinson's who are at risk of experiencing restrictive respiratory problems is unknown. The aim of this study is to examine the effects of spinal mobilization techniques for the diaphragm on respiratory function parameters and posture.

Conditions reported: Parkinson Disease; Camptocormia; Restrictive Lung Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Diaphragmatic stimulation treatment with PNF techniques; Costal mobilization; Breathing exercises; Spinal mobilization; Sham mobilization
Phases
NA
Sponsor
Abant Izzet Baysal University
Start date reported by registry
2021-08-15 (actual)

Registry updated: 2025-06-22 · Status last verified by the registry submitter: 2025-06

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Ramazan Kurul, Ph.D · +905436414731 · ramazankurul2@hotmail.com

Enes Tayyip Benli, MSc · +905387359268 · enestayyipbenli@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Abant Izzet Baysal University Faculty of Health Science

Bolu, Turkey (Türkiye)

Not yet recruiting

Ramazan Kurul, Ph.D · +905436414731 · ramazankurul2@hotmail.com

Enes Tayyip Benli, MSc · +905387359268 · enestayyipbenli@gmail.com

AIBU Physical Therapy and Rehabiltiation Department

Bolu, Turkey (Türkiye)

Recruiting

Ramazan Kurul, Ph.D

Facility not reported

Turkey (Türkiye)

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.