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Measuring eye movements in Parkinson’s

Researchers record eye movements in people with mild to moderate Parkinson’s to learn how eye movement patterns relate to the condition.

Testing a treatment or activity · Study reference: NCT04731246

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2021-07-07
Main measurements finished (planned)
2032-01
Study finished (planned)
2032-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

\*Inclusion Criteria: 1. Male or Female; 2. Clinically defined idiopathic Parkinson's Disease (PD); 3. Brain MRI performed in routine care in the 12 months preceding inclusion; 4. Cerebral DaTSCAN or cerebral PET with F-DOPA, performed as routine care before inclusion (no time limit), confirming presynaptic dopaminergic denervation; 5. Hoehn \& Yahr score: 1 to 3; 6. Normal clinical examination of oculomotricity (slight impairment of smooth pursuit accepted); 7. Neuro-cognitive disorders: absent or minor (according to DSM5); 8. Sufficient written and oral expression in French; 9. Covered by a health insurance system; 10. Written informed consent signed by the patient; 11. Presence of a caregiver. \* Exclusion Criteria: 12. Psychiatric comorbidity (except anxiety or mild to moderate depression); 13. Neurological comorbidity, if significant; 14. Brain MRI showing: 1. significant cerebrovascular pathology (Fazekas I admitted), 2. another brain disease, including stroke. 15. Major cognitive impairment; 16. Absolute exclusion criteria and "Red flags" of the 2015 criteria orienting towards another degenerative pathology of the extrapyramidal system: * Cerebellar syndrome * Vertical oculomotricity disorders on clinical examination * Motor symptoms restricted to the lower limbs * Bilateral and perfectly symmetrical parkinsonism * Early dystonia * Clinical profile suggestive of behavioral variant frontotemporal dementia (bvFTD) * Progressive aphasia or apraxia * Moderate or severe postural instability and / or early falls * Early bulbar dysfunction (dysarthria, swallowing disorders) * Ventilatory dysfunction (inspiration) * Severe dysautonomia * DOPA-resistance * Neuroleptic treatment or related 17. Normal MIBG myocardial scintigraphy (if performed).
Full study name & original research details

Official study title

Video-oculography and Parkinson's Disease: A Prospective Study

Short title used by the registry

Video-oculography and Parkinson's Disease

Original description

This study aims to study, in patient with Parkinson's disease, mild to moderate stage (according to Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease, Postuma et al., 2015): * the evolution of oculomotricity markers over time. * the correlation between neurological evaluations (motor and non-motor scores), neuropsychological evaluations (cognitive disorders) and oculomotricity evaluation, over a follow-up period of 7 years. * the impact of antiparkinsonian drugs on the evolution of oculomotricity assessment by video-oculography. * the value of oculomotricity assessment by video-oculography as an evolutionary marker of the disease.

Conditions reported: Parkinson Disease, Idiopathic

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Video-oculography / Neuropsychological evaluations
Phases
NA
Sponsor
Association de Recherche Bibliographique pour les Neurosciences
Start date reported by registry
2021-07-07 (actual)

Registry updated: 2025-10-01 · Status last verified by the registry submitter: 2025-09

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Solange HESSE · +377 99995599 · solange.hesse@chpg.mc

Kévin POLET · kevin.polet@chpg.mc

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Centre Mémoire / Centre de Gérontologie Clinique Rainier III / Princess Grace Hospital

Monaco, Monaco

Recruiting

Solange HESSE · +377 99995599 · solange.hesse@chpg.mc

Kevin POLET · kevin.polet@chpg.mc

Sandrine LOUCHART DE LA CHAPELLE, MD-PHD

Facility not reported

Monaco

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.