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Rehabilitation games at home for walking and balance

Researchers compare home rehabilitation using purpose-designed games with another approach, examining effects and costs in Parkinson’s.

Testing a treatment or activity · Study reference: NCT04720365

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2023-02-15
Main measurements finished (planned)
2029-02-01
Study finished (planned)
2029-02-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: 1. Diagnosis of idiopathic Parkinson's disease (according to United Kingdom Parkinson's Disease Society Brain Bank \[UKPDD\] criteria) ; 2. Age ≥ 18 years ; 3. Patient with gait and/or balance disorders not improved by levodopa treatment with item 12 "walking and balance" ≥ 1 of the MDS-UPDRS (Movement-Disorders Society-Unified Parkinson's disease rating scale) part II, ON levodopa and/or item 13 of "gait freezing" ≥ 1 (Goetz, Tilley et al. 2008); 4. Number of falls ≥ 2 in the previous year; 5. Stable antiparkinsonian treatments for at least 1 month prior to inclusion in the study ; 6. Patient with social health insurance ; 7. Person who voluntarily and informedly agreed to participate in the study (signed written consent) ; 8. Other medical problems that are stable or do not interfere with the proposed protocol; Exclusion Criteria: 1. Parkinson's disease with Hoehn\&Yahr stage 5 corresponding to an inability of the subject to stand or walk alone ; 2. Dementia (MMS \< 24 and/or MoCA \< 18) ; 3. Presence of an impulse control disorder defined by item 6 of the MDS-UPDRS part I \> 2 ; 4. Absence of internet connection at home ; 5. Serious pathology interfering with the test ; 6. Estimated life expectancy of less than 2 years ; 7. Subject in a period of exclusion from further research ; 8. Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights and liberty ; 9. Pregnant woman or woman of childbearing age without contraceptive methods;
Full study name & original research details

Official study title

Medico-economic Evaluation Rehabilitation by Serious Games at Home for the Management of Patients With Parkinson's Disease Suffering From Gait and Balance Disorders

Original description

This is a multi-center, randomized, open-label, multi-center, randomized controlled study of 80 Parkinson's disease patients with gait and balance disorders in which 40 patients will be treated with serious games, in addition to their usual care, for 12 months and 40 patients will be treated with their usual care during this period. This study will be conducted in 4 centers, all of which are expert in the management of these patients. After randomization, each patient in the "Intervention-Rehabilitation through Toap Run" group will have to complete 2 to 3 sessions per week at home with the serious game "TOAP RUN" using the Kinect® system for 1 year.

Further description from the registry

This is a multi-center, randomized, open-label, multi-center, randomized controlled study of 80 Parkinson's disease patients with gait and balance disorders in which 40 patients will be treated with serious games, in addition to their usual care, for 12 months and 40 patients will be treated with their usual care during this period. This study will be conducted in 4 centers, all of which are expert in the management of these patients. After randomization, each patient in the "Intervention-Rehabilitation through Toap Run" group will have to complete 2 to 3 sessions per week at home with the serious game "TOAP RUN" using the Kinect® system for 1 year. The primary endpoint is a medical-economic endpoint: the difference in incremental cost-utility ratio at 12 months between the 2 groups of patients. Costs will be assessed at inclusion, at the end of 6 and 12 months. Secondary endpoints include clinical and neurophysiological assessments, focusing on gait and balance disorders, as well as cognition and emotional state. An imaging study for patients included in the Paris-ICM center is also planned to study the effects of serious game rehabilitation on brain function. Patients in both groups will be free to use SG at the end of the intervention.

Conditions reported: Patients With Parkinson's Disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
play-based rehabilitaion
Phases
NA
Sponsor
University Hospital, Rouen
Start date reported by registry
2023-02-15 (actual)

Registry updated: 2026-02-06 · Status last verified by the registry submitter: 2026-02

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Nell Marty · (33) 02 32 88 82 65 · Nell.Marty@chu-rouen.fr

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Chu Bordeaux

Bordeaux, France

Recruiting

Dominique Guehl, Pr · 05 57 57 15 51 · dominique.guehl@ubordeaux2.fr

Dominique Guehl, Pr

Chu Lille

Lille, France

Recruiting

Caroline Moreau, Pr · 03 20 44 59 62 · caroline.moreau@chru-lille.fr

Caroline Moreau, Pr

Gh Pitie Salpetriere

Paris, France

Recruiting

Louise Laure Mariani, Dr · 01 42 17 62 05 · louiselaure.mariani@aphp.fr

Louise Laure Mariani, Dr

Rouen University Hospital

Rouen, France

Recruiting

Marie-Laure WELTER, Professor · 02 32 88 80 37 · Marie-Laure.Welter@chu-rouen.fr

Marie-Laure Welter, Pr

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.