RESEARCH / PARTICIPATIONBack to the library
← Find a study
Completed · registry status

Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson's Disease

A plain-language introduction is being prepared for this study. Open it to read the original description, who can join and how to contact the team.

Testing a treatment or activity · Study reference: NCT04379050

The registry title is shown while an English plain-language introduction is prepared. Read the original details below ↓

Open the official registry record ↗

Follow this study

Completed; watching for results

Start (reported actual date)
2020-06-08
Main measurements finished (reported actual date)
2026-04-17
Study finished (reported actual date)
2026-04-17

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — completed

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

Real-World Safety and Effectiveness of 24-Hour Foslevodopa/Foscarbidopa in Parkinson's Disease: ROSSINI Study 6-Month Interim Results.
This paper mentions the study ID; the relationship needs review · 2026

Participation rules recorded for this study

Age 30 years and over · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Participants who have Parkinson's Disease and who have successfully completed the parent study M15-741. * Participants willing and able to comply with procedures required in the protocol. Exclusion Criteria: \- Participants, if judged by the investigator to be unsuitable candidates to continue to receive ABBV-951 for any reason.
Full study name & original research details

Official study title

An Open-label Extension of Study M15-741 to Evaluate the Safety and Tolerability of 24-hour Daily Exposure of Continuous Subcutaneous Infusion of ABBV-951 in Subjects With Parkinson's Disease

Short title used by the registry

Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson's Disease

Original description

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. The purpose of this study is to continue testing whether ABBV-951 is safe, effective, and tolerable in participants with Parkinson's disease after completion of the parent study M15-741. ABBV-951 is an investigational (unapproved) drug containing levodopa phosphate/carbidopa phosphate (LDP/CDP) given as infusion under the skin for the treatment of Parkinson's Disease. Participants who have successfully completed M15-741 study will immediately enter this study's treatment period to continue receiving ABBV-951. Adult participants with advanced PD will be enrolled. Approximately 130 adult participants will be enrolled in the study at approximately 65 sites worldwide. Participants will receive continuous subcutaneous infusion (CSCI) of ABBV-951 for 24 hours daily during the Primary Treatment Period and during the optional Extended Treatment Period. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular clinic visits and have remote assessments completed via phone calls during the course of the study. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects, and completing questionnaires.

Conditions reported: Parkinson's Disease (PD)

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
ABBV-951
Phases
PHASE3
Sponsor
AbbVie
Start date reported by registry
2020-06-08 (actual)

Registry updated: 2026-05-13 · Status last verified by the registry submitter: 2026-05

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

No central contact is listed. Check the location contacts or the official registry record.

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

University of Alabama at Birmingham - Main /ID# 215597

Birmingham, Alabama, United States

Status not reported

Banner Sun Health Research Institute /ID# 215579

Sun City, Arizona, United States

Status not reported

University of Colorado Hospital /ID# 215625

Aurora, Colorado, United States

Status not reported

Parkinson's Disease and Movement Disorders Center of Boca Raton /ID# 215412

Boca Raton, Florida, United States

Status not reported

Indiana Clinical Research Cent /ID# 216490

Indianapolis, Indiana, United States

Status not reported

Univ Kansas Med Ctr /ID# 215624

Kansas City, Kansas, United States

Status not reported

Washington University-School of Medicine /ID# 215472

St Louis, Missouri, United States

Status not reported

Dartmouth-Hitchcock Medical Center /ID# 216834

Lebanon, New Hampshire, United States

Status not reported

M3 Wake Research - Raleigh /ID# 215596

Raleigh, North Carolina, United States

Status not reported

Legacy Medical Group - Neurology /ID# 215536

Portland, Oregon, United States

Status not reported

Baylor College of Medicine /ID# 215401

Houston, Texas, United States

Status not reported

Central Texas Neurology Consul /ID# 217013

Round Rock, Texas, United States

Status not reported

Univ Texas HSC San Antonio /ID# 215400

San Antonio, Texas, United States

Status not reported

Booth Gardner Parkinson's Care Center /ID# 215535

Kirkland, Washington, United States

Status not reported

Inland Northwest Research /ID# 215533

Spokane, Washington, United States

Status not reported

Concord Repatriation General Hospital /ID# 215943

Concord, New South Wales, Australia

Status not reported

Westmead Hospital /ID# 215941

Westmead, New South Wales, Australia

Status not reported

Duplicate_Royal Adelaide Hospital /ID# 215940

Adelaide, South Australia, Australia

Status not reported

The Alfred Hospital /ID# 215942

Melbourne, Victoria, Australia

Status not reported

Perron Institute /ID# 215944

Nedlands, Western Australia, Australia

Status not reported

Universitair Ziekenhuis Leuven /ID# 215684

Leuven, Vlaams-Brabant, Belgium

Status not reported

Duplicate_Algemeen Ziekenhuis Sint-Jan Brugge /ID# 215686

Bruges, West-Vlaanderen, Belgium

Status not reported

Duplicate_Groupe Sante CHC - Clinique du MontLegia /ID# 215685

Liège, Belgium

Status not reported

University of Calgary /ID# 215369

Calgary, Alberta, Canada

Status not reported

Clinique Neuro Levis /ID# 215371

Lévis, Quebec, Canada

Status not reported

Bispebjerg and Frederiksberg Hospital /ID# 215391

Copenhagen NV, Capital Region, Denmark

Status not reported

Aarhus Universitetshospital - Skejby /ID# 215392

Aarhus, Central Jutland, Denmark

Status not reported

Odense University Hospital /ID# 215390

Odense, Region Syddanmark, Denmark

Status not reported

Universitaetsklinikum Ulm /ID# 215405

Ulm, Baden-Wurttemberg, Germany

Status not reported

curiositas ad sanum /ID# 215404

Haag i.OB, Bavaria, Germany

Status not reported

Kliniken Beelitz GmbH /ID# 215403

Beelitz-Heilstätten, Germany

Status not reported

IRCCS Centro Neurolesi Bonino Pulejo /ID# 215422

Messina, Italy

Status not reported

Azienda Ospedale-Universita Padova /ID# 215421

Padova, Italy

Status not reported

National Hospital Organization Asahikawa Medical Center /ID# 218762

Asahikawa-shi, Hokkaido, Japan

Status not reported

Duplicate_Osaka University Hospital /ID# 217415

Suita-shi, Osaka, Japan

Status not reported

National Center of Neurology and Psychiatry /ID# 218763

Kodaira-shi, Tokyo, Japan

Status not reported

St. Antonius Ziekenhuis, Locatie Utrecht /ID# 215396

Utrecht, Netherlands

Status not reported

Academician I.P. Pavlov First St. Petersburg State Medical University /ID# 218869

Saint Petersburg, Sankt-Peterburg, Russia

Status not reported

City Clinical Hospital #40 /ID# 218870

Sestroretsk, Sankt-Peterburg, Russia

Status not reported

Complejo Hospitalario Universitario A Coruña /ID# 215426

A Coruña, A Coruna, Spain

Status not reported

Hospital General Universitario de Elche /ID# 215425

Elche, Alicante, Spain

Status not reported

Hospital Universitari de Bellvitge /ID# 215427

L'Hospitalet de Llobregat, Barcelona, Spain

Status not reported

Hospital Santa Creu i Sant Pau /ID# 215429

Barcelona, Spain

Status not reported

Hospital Universitario Virgen de las Nieves /ID# 215431

Granada, Spain

Status not reported

Hospital Universitario Virgen del Rocio /ID# 215428

Seville, Spain

Status not reported

Skane University Hospital Lund /ID# 215385

Lund, Skåne County, Sweden

Status not reported

Karolinska Universitetssjukhuset - Huddinge /ID# 215386

Huddinge, Stockholm County, Sweden

Status not reported

Sahlgrenska Universitetssjukhuset /ID# 215387

Gothenburg, Västra Götaland County, Sweden

Status not reported

Derriford Hospital and the Royal Eye Infirmary /ID# 217390

Plymouth, Devon, United Kingdom

Status not reported

Kings College Hospital NHS Foundation Trust /ID# 217388

London, Greater London, United Kingdom

Status not reported

NHS Tayside /ID# 217389

Dundee, Scotland, United Kingdom

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.