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Understanding the brain networks for speaking and listening

Researchers record brain activity to learn how the brain processes speech and produces it.

Testing a treatment or activity · Study reference: NCT04286308

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported actual date)
2020-10-01
Main measurements finished (planned)
2027-02
Study finished (planned)
2027-02

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 85 years · Does not accept healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: 1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia. 2. Subjects able to provide informed consent and comply with task instructions. 3. Subjects 18-85 years old Exclusion Criteria: 1. Subjects with reported hearing loss. 2. Non-English-speaking subjects
Full study name & original research details

Official study title

Cortical-Basal Ganglia Speech Networks

Original description

In this research study the researchers want to learn more about brain activity related to speech perception and production.

Further description from the registry

Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.

Conditions reported: Parkinson Disease; Essential Tremor; Dystonia

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
electrophysiological data collection
Phases
NA
Sponsor
Massachusetts General Hospital
Start date reported by registry
2020-10-01 (actual)

Registry updated: 2026-03-25 · Status last verified by the registry submitter: 2026-01

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Mark Richardson, MD, PhD · 617-726-8849 · mark.richardson@mgh.harvard.edu

Erin Donahue, PhD · ekdonahue@mgh.harvard.edu

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Massachusetts General Hospital

Boston, Massachusetts, United States

Recruiting

Robert M Richardson, MD PhD · 617-726-8849 · mark.richardson@mgh.harvard.edu

Erin Donahue, PhD · ekdonahue@mgh.harvard.edu

Facility not reported

United States

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.