Recruiting · registry status

Following different forms of dementia

Researchers assess people with several types of dementia and a comparison group without thinking difficulties, following changes over time.

Learning by observing or collecting information · Study reference: NCT03402919

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported actual date): 2016-06
Main measurements finished (reported actual date): 2023-11
Study finished (planned): 2029-12

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

Montero-Odasso M, Sarquis-Adamson Y, Kamkar N, Pieruccini-Faria F, Bray N, Cullen S, Mahon J, Titus J, Camicioli R, Borrie MJ, Bherer L, Speechley M. Dual-task gait speed assessments with an electronic walkway and a stopwatch in older adults. A reliability study. Exp Gerontol. 2020 Dec;142:111102. doi: 10.1016/j.exger.2020.111102. Epub 2020 Oct 2. ↗
Registry derived research reference

Who can join?

Ages 50 years to 90 years · Also accepts healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * Has subjective or objective cognitive impairment * Written informed consent must be obtained and documented (from the patient or, where jurisdictions allow it, from a caregiver/family member) * Sufficient proficiency in English or French to undertake self report and neuropsychological testing * Geographic accessibility to the study site * Must have a study partner who can participate as required in the protocol (provide corroborative information) * Up to 12 years of education * Fits into one of the following groups: Cognitively Unimpaired, Subjective Cognitive Impairment, Mild Cognitive Impairment, Vascular Mild Cognitive Impairment, Parkinson's Disease, Parkinson's Disease with Mild Cognitive Impairment Exclusion Criteria: * The presence of other significant known chronic brain disease such as: moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, a serious developmental handicap, malignant tumors, Parkinson's disease (other than for the Parkinson's cohort), and other rarer brain illnesses * Ongoing alcohol or drug abuse which in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures * Symptomatic stroke within the previous year * Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure

Full study name & original research details

Official study title

The Comprehensive Assessment of Neurodegeneration and Dementia Study

Short title used by the registry

Comprehensive Assessment of Neurodegeneration and Dementia

Original description

This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits. Participants are/will be recruited at sites across Canada and will undergo assessments, neuroimaging, and biological sample collection.

Further description from the registry

This is a longitudinal observational study that started in Phase I with the recruitment of 1173 participants between the ages of 50 and 90 years with Subjective Cognitive Impairment, Mild Cognitive Impairment, Mild Cognitive Impairment with subcortical vascular lesions, Alzheimer's Disease, Mixed dementia, Lewy Body Dementia, Parkinson's Disease Dementia, Parkinson's Disease with Mild Cognitive Impairment and Frontotemporal Dementia as well as healthy elderly subjects without cognitive complaints or deficits. These participants were enrolled in 30 different centres across Canada. All subjects involved in the study underwent rigorous evaluations at baseline, including clinical assessment, neuropsychological assessment, genomics and neuroimaging. Biological samples from blood, saliva, urine, fecal matter, buccal cells and cerebrospinal fluid were collected, stored, and analyzed. Longitudinal follow-up determining if there has been any change in their diagnosis was carried out annually and longitudinal re-evaluation was carried out at two times: Time 2 and Time 3. In Time 3, 400 participants across the non-dementia cohorts (Cognitively Unimpaired, Subjective Cognitive Impairment, Mild Cognitive Impairment, Mild Cognitive Impairment with a Vascular Component, Parkinson's Disease with no Cognitive Impairment, Parkinson's Disease with Mild Cognitive Impairment) with up to 12 years of education will be recruited.

Conditions reported: Dementia; Mild Cognitive Impairment (MCI); Subjective Cognitive Impairment; Parkinson's Disease (PD); Lewy Body Disease(LBD); Mixed Dementia; Frontotemporal Dementia (FTD); Alzheimer Disease (AD); Cognitively Unimpaired; Subjective Cognitive Decline (SCD)

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT03402919 ↗ — RECRUITING; checked 2026-10-13

Study type: Observational
Interventions: Not reported
Phases: Not reported
Sponsor: McGill University
Start date reported by registry: 2016-06 (actual)

Registry updated: 2026-01-20 · Status last verified by the registry submitter: 2025-11

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Howard Chertkow, MD · 514 340 8222 · howard.chertkow@mcgill.ca

Randi Pilon · 514 8339709 · Randi.Pilon@ladydavis.ca

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

University of Calgary

Calgary, Alberta, Canada

Recruiting

Eric E Smith, MD · 403.944.1594 · eric.smith@albertahealthservices.ca

University of Alberta Hospital

Edmonton, Alberta, Canada

Recruiting

Richard Camicioli, MD · (780) 248-1774 · rcamicio@ualberta.ca

Krista Nelles, B. A. · (780) 248-2043 · knelles@ualberta.ca

Djavad Mowafaghian Centre for Brain Health

Vancouver, British Columbia, Canada

Recruiting

Robin Hsiung, MD · 604-822-3610 · hsiung@mail.ubc.ca

Mannie Fan, M.Sc. · 604-822-0550 · mannie.fan@vch.ca

Island Health

Victoria, British Columbia, Canada

Not yet recruiting

Alexandre Henri-Bhargava, MD · (778) 265-6111 · alexhb@uvic.ca

Karen Coles, RN · 250.370-8111 · karen.coles@viha.ca

Veteran's Memorial Building

Halifax, Nova Scotia, Canada

Recruiting

Maia von Maltzahn, MD · 902-473-2495 · Maia.Maltzahn@nshealth.ca

Jodie Penwarden, MFSGN · 902-473-7705 · Jodie.Penwarden@nshealth.ca

Hamilton General Hospital

Hamilton, Ontario, Canada

Recruiting

Demetrios Sahlas, MD · 905-521-2100 · sahlas@mcmaster.ca

St. Joseph's Health Care London

London, Ontario, Canada

Recruiting

Michael Borrie, MD · (519) 685-4021 · michael.borrie@sjhc.london.on.ca

Kayla Vander Ploeg · kayla.vanderploeg@sjhc.london.on.ca

Gait and Brain Lab

London, Ontario, Canada

Recruiting

Manuel Montero-Odasso, MD · 519.685.4292 · mmontero@uwo.ca

Abbie Barron, BA · 519.685.4292 · Abbie.Barron@sjhc.london.on.ca

Bruyère Research Institute

Ottawa, Ontario, Canada

In progress; recruitment closed

Kawartha Centre

Peterborough, Ontario, Canada

In progress; recruitment closed

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada

In progress; recruitment closed

University Health Network Memory Clinic

Toronto, Ontario, Canada

In progress; recruitment closed

Baycrest Clinical Unit

Toronto, Ontario, Canada

Recruiting

Howard Chertkow, PhD · (416)785-2500 · howard.chertkow@mcgill.ca

Paramjeet Sandhu · (416) 785-2500 · psandhu@research.baycrest.org

University of Waterloo

Waterloo, Ontario, Canada

In progress; recruitment closed

Research Institute of the McGill University Health Centre

Montreal, Quebec, Canada

In progress; recruitment closed

Jewish General Hospital/McGill Memory Clinic

Montreal, Quebec, Canada

Recruiting

Susan Vaitekunas, MD · 514 340 8222 · svaitekunas@jgh.mcgill.ca

Chris Hosein, M.Ed · 514 304 8222 · chosein@jgh.mcgill.ca

Clinique de cognition Institut universitaire de gériatrie de Montréal

Montreal, Quebec, Canada

Recruiting

Marie-Jeanne Kergoat, MD · 514 340-3540 · marie-jeanne.kergoat@umontreal.ca

Sylvie Belleville · sylvie.belleville@umontreal.ca

Hôpital Enfant-Jésus

Québec, Quebec, Canada

Recruiting

Louis Verret, MD · 418-649-5980 · verretl@videotron.ca

Nancy Parent, RN · 418 649-0252 · nancy.parent.cha@ssss.gouv.qc.ca

Centre de recherche sur le vieillissement CIUSSS de l'Estrie-CHUS

Sherbrooke, Quebec, Canada

In progress; recruitment closed

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.