Recruiting · registry status

Using brain scans to understand dementia in Parkinson’s

Researchers use specialised scans to study differences in brain changes associated with dementia in people with Parkinson’s.

Learning by observing or collecting information · Study reference: NCT02763683

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported date): 2016-06
Main measurements finished (planned): 2030-03
Study finished (planned): 2030-03

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 50 years and over · Also accepts healthy volunteers

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion Criteria: * PD patients must exhibit three of the following cardinal signs: rest tremor, rigidity, bradykinesia, or postural instability; or two of these features with one of the first three displaying asymmetry. Exclusion Criteria: * history of head trauma, major neurological or psychiatric diseases other than Parkinson disease and dementia, e.g. stroke, multiple sclerosis, depression or schizophrenia. * severe systemic diseases. * inability to lie still for 90 minutes. * metallic implants, pacemakers, or any other contraindication to MRI. * refusal to consent to brain donation.

Full study name & original research details

Official study title

Investigations of Dementia in Parkinson Disease

Original description

The purpose of this study is to use a brain imaging method called Pittsburgh B (PIB) Positron Emission Tomography (PET) and Vesicular Cholinergic Transport (VAT) PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with PD who are at risk of developing dementia, and to distinguish the underlying cause of dementia.

Further description from the registry

The purpose of this study is to use a brain imaging method called PIB PET and VAT PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with PD who are at risk of developing dementia, and to distinguish the underlying cause of dementia. The investigators will be including both PD and normal subjects in this study. This a long term study and we are considering including a total of 320 participants in this protocol.

Conditions reported: Parkinsons

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ClinicalTrials.gov · NCT02763683 ↗ — RECRUITING; checked 2026-10-11
ClinicalTrials.gov · NCT02763683 ↗ — Recruiting; WHO ICTRP processed 2026-05-18; checked 2026-10-11

Study type: Observational
Interventions: PiB and VAT
Phases: Not reported
Sponsor: Washington University School of Medicine
Start date reported by registry: 2016-06 (Not reported)

Registry updated: 2026-05-08 · Status last verified by the registry submitter: 2026-05

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Andrea Slavik, RN, BSN · 314 273 8313 · andreaslavik@wustl.edu

Hailee Domash · 314 362 6026 · domash@wustl.edu

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Washington University in St. Louis

St Louis, Missouri, United States

Recruiting

Susan Donovan, BSN · 314-362-6026 · donovan@wustl.edu

Kaleigh Oberndorfer · 314 362 0420 · kaleigh@wustl.edu

Facility not reported

United States

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.