Recruiting · registry status

Activity trackers and exercise videos

Researchers are studying a home exercise approach using activity trackers and video guidance for people with Parkinson's.

Testing a treatment or activity · Study reference: JPRN-jRCT1030220416

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported date): 2022-10-27

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages >= 40age old to <= 80age old · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: 1. Patient (Hoehn and Yahr I,II) with diagnosis of Parkinson disease according to the 2015 MDS (International Parkinson and Movement Disorder Society) crinical diagnostic criteria of Parkinson disease. 2. Able to come to Juntendo University Koshigaya hospital regularly during the study period. 3. Older than 40 years old and yonger than 80 years old with no dementia criteria of a MMSE at a baseline >= 26. Exclusion criteria: 1.Yonger than 39 years old and older than 81 years old. 2.Patient with diagnosis of cerebrovascular disease, neuroimmunological disease, seizure disorder and neurodegenerative disease, such multiple system atrophy, progressive supranuclear pulsy and Alzheimer disease. 3.Patient with an abnormal ECG or past medical history of coronary infarction. Patient with an obvious orthostatic hypotension. 4.Patient with a hepatic disorder, a renal disorder and malignancy. 5.Others that investigators judged inappropriate.

Full study name & original research details

Official study title

Validation of neuroprotective factors reflecting exercise effects in patients with Parkinson disease.

Short title used by the registry

Validation of exercise effects in patients with Parkinson disease.

Original description

Intervention: We will destribute activity tracker (acti graph) to recruited and randomized patients with Parkinson disease. Group of exercise; DVD exercise (about 30minutes) and 20 minutes walking at least 5 times/ a week. Group of no exercise / sedentary; Usual daily living activity. We will measure activity 1month (+/-2 weeks) before as a baseline and 1,3,6,9 month after starting exercise. We will keep the score of clinical evaluation, collect patients blood samples and measure candidate neuroprotective factors mentioned below with the period of 1month (+/-2 weeks) before and 1,3,6,9 month after starting exercise.;D015444, D016138,D009043;exercise, walking, activity Primary outcome: Protein and mRNA amount of mitochondrial protein deacetylase SIRT3 in blood samples of randomly assigned patients in exercise and no exercise group. Secondary outcome: Clinical evaluation; MDS-UPDRS part 3 (movement function scale), MMSE (dementia scale), HAMD (depression scale), non-motor symptoms assessment scale (NMSS). Candidate neuroprotective factors; anti-alpha synuclein antibody, Brain-derived neurotrophic factor (BDNF), Vascular endothelial growth factor (VEGF), DNA methylase 1 (Dnmt1), alpha-synuclein DNA methylation rate.

Conditions reported: Parkinson's disease;D010300

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

JPRN · JPRN-jRCT1030220416 ↗ — Recruiting; WHO ICTRP processed 2026-06-29; checked 2026-10-13

Study type: Interventional
Interventions: We will destribute activity tracker (acti graph) to recruited and randomized patients with Parkinson disease. Group of exercise; DVD exercise (about 30minutes) and 20 minutes walking at least 5 times/ a week. Group of no exercise / sedentary; Usual daily living activity. We will measure activity 1month (+/-2 weeks) before as a baseline and 1,3,6,9 month after starting exercise. We will keep the score of clinical evaluation, collect patients blood samples and measure candidate neuroprotective factors mentioned below with the period of 1month (+/-2 weeks) before and 1,3,6,9 month after starting exercise.;D015444, D016138,D009043;exercise, walking, activity
Phases: N/A
Sponsor: Ando Maya
Start date reported by registry: 2022-10-27 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-13 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Maya Ando · +81-48-975-0321 · my-ando@juntendo.ac.jp

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

No locations reported. Ask the study team where participation is available.

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.