Recruiting · registry status

Scanning the brain's support cells

This study uses specialised scans to investigate brain support cells in dementia and psychiatric conditions.

Testing a treatment or activity · Study reference: JPRN-UMIN000053565

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Results reported

Start (reported date): 2024-03-01
Study finished (reported date): 2028-03-31

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Changes we have recorded

2026-10-11 — recruiting

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Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18years-old to 95years-old · Ask the team who can join

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Sex eligibility reported by registry: male and female

Inclusion criteria: Demnetiing disease patients who met the clinical criteria of the MCI, AD, DLB, PD, FTD, PSP, CBD, MSA, high cortical dysfunction. Healthy subjects whose ADL is normal. All participants who are able to scan PET imaging. Exclusion criteria: 1, Pregnant, possibly pregnant or lactating women 2, Subjects with claustrophobia 3, patient who had the illness which influence the results of PET study 4, patient who was medicated the drugs which influence the results of PET study 5, Patient with DM whose BS was more than 240mg/dL 6, Subjects who are considered to be inappropriate for participation by the doctors with responsibilities in this study

Full study name & original research details

Official study title

Astrocyte imaging study using positron emission tomography with [11C]BU99008 for dementia and psychiatric disease - Astrocyte imaging study using positron emission tomography with [11C]BU99008 for dementia and psychiatric disease

Short title used by the registry

Astrocyte imaging study using positron emission tomography for dementia and psychiatric disease

Original description

Intervention: 1, intravenous injection of 370MBq dose of [11C]BU99008 2, intravenous injection of 370MBq dose of[11C]DPA713 3, intravenous injection of 185MBq of [18F]BCPP-EF Primary outcome: quantitative analysis of the distribution of the [11C]BU99008 Secondary outcome: correlation of reactive astrocyte with cognitive decline, activated microglia, and mitochondrial dysfunction

Conditions reported: Alzheimer's disease, dementia with lewy body(Parkinson's disease), fronto-temporal dementia, progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, high cortical dysfunction, and mild cognitive impairments

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

JPRN · JPRN-UMIN000053565 ↗ — Recruiting; WHO ICTRP processed 2026-06-29; checked 2026-10-11

Study type: Interventional
Interventions: 1, intravenous injection of 370MBq dose of [11C]BU99008 2, intravenous injection of 370MBq dose of[11C]DPA713 3, intravenous injection of 185MBq of [18F]BCPP-EF
Phases: Not selected
Sponsor: Hamamatsu University School of Medicine
Start date reported by registry: 2024-03-01 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Tatsuhiro Terada · 053-435-2261 · tatuhiro@hama-med.ac.jp

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Japan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.