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Brain protein build-up in Parkinson's-related dementia

This study examines amyloid, a protein that can build up in the brain, in Parkinson's dementia and Lewy body dementia.

Learning by observing or collecting information · Study reference: JPRN-UMIN000047904

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Results reported

Start (reported date)
2022-05-25
Study finished (reported date)
2024-03-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

Read the results reported in the registry

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 40years-old to 80years-old · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: male and female

Inclusion criteria: Patients with PDD or DLB who are attending or being admitted to the Department of Neurology, Juntendo University Hospital, Juntendo University School of Medicine, will be included in the study. PDD is diagnosed as Clinically Established PD or Clinically Probable PD by MDS Clinical Diagnostic Criteria for Parkinson's Disease, and PDD is defined as the onset of Dementia 2 years later. DLB is defined as patients diagnosed with Probable DLB (almost certain) by the Clinical Diagnostic Criteria for Dementia with Lewy Bodies (2017) Amyloid PET and neuropsychological testing can be performed For whom 123I-Ioflupane SPECT testing has been performed IMP-SPECT test performed has been performed Exclusion criteria: Age less than 40 years and greater than 81 years at the time consent was obtained Patients with more than moderate multiple cerebral infarctions Those with a history of epileptic seizures within 2 years Other subjects deemed inappropriate as research subjects by the principal investigator
Full study name & original research details

Official study title

Clinical research to evaluate beta-amyloid deposition in the brain of patients with Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB) - Amyloid PET studies in PDD and DLB

Short title used by the registry

Clinical research to evaluate beta-amyloid deposition in the brain of patients with Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB)

Original description

Primary outcome: beta-amyloid deposition in the brain

Conditions reported: Parkinson's disease with dementia (PDD) Dementia with Lewy bodies (DLB)

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Not reported
Phases
Not selected
Sponsor
Juntendo University School of Medicine
Start date reported by registry
2022-05-25 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Noriko Nishikawa · 03-3813-3111 · n.nishikawa.ts@juntendo.ac.jp

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Japan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.