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Finding measurable signs of neurological disease

This study combines symptom assessments, thinking tests, scans and laboratory measures to investigate Parkinson's and related conditions.

Learning by observing or collecting information · Study reference: JPRN-UMIN000036570

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Results reported

Start (reported date)
2014-05-08
Study finished (reported date)
2025-03-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

Read the results reported in the registry

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18years-old and over · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: male and female

Inclusion criteria: Patients over 18 years old with parkinsonism, who provided (by own or by a representative) a written informed consent. Parkinsonism is defined as two or more symptoms in tremor, akinesia, muscular rigidity, and postural reflex disorder, which show a slow progressive course. As a disease control, this study also targets at patients who receive spinal fluid drainage to prevent spinal cord ischemia among thoracoabdominal surgery. Exclusion criteria: None
Full study name & original research details

Official study title

Prospective and exploratory study for disease specific biomarkers and objective indicators in neurodegenerative diseases - Prospective study for biomarkers in neurodegenerative diseases

Short title used by the registry

Prospective and exploratory study for disease specific biomarkers and objective indicators in neurodegenerative diseases

Original description

Primary outcome: Assessment of parkinsonism (MDS-UPDRS score, Hoehn-Yahr stage) Secondary outcome: Cognitive evaluation (MMSE, Visual Perspective test, etc.), Brain imaging evaluation (structural MRI , functional MRI, etc.) and biochemical markers of cerebrospinal fluid and serum (catecholamine concentration, alpha-synuclein concentration, cerebrospinal fluid amyloid aggregation, etc.)

Conditions reported: All Neurodegenerative diseases specifically Parkinson's disease, corticobasal degeneration and progressive supranuclear palsy

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Not reported
Phases
Not applicable
Sponsor
Department of Neurology, Osaka University Graduate School of Medicine
Start date reported by registry
2014-05-08 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Kotaro Ogawa · +(81)-6-6879-3571 · crgou@neurol.med.osaka-u.ac.jp

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Japan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.