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Following early signs that might precede Parkinson's

This study follows people with symptoms beyond movement problems to investigate whether tests can help identify Parkinson's earlier.

Testing a treatment or activity · Study reference: JPRN-UMIN000030396

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Results reported

Start (reported date)
2018-03-31
Study finished (reported date)
2029-03-31

Planned dates can move. A study finishing does not tell us when a paper will be published.

Read the results reported in the registry

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 50years-old and over · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: male and female

Inclusion criteria: Examinees of medical checkups who answered the questionnaire about non-motor symptoms of Parkinson disease Subjects who can make a outpatient visit regularly Subjects who agreed to participate in this study Subjects who fulfill one of the following criteria 1) participants who have two or more non-motor symptoms: SCOPAAUT, 10 or more; SAOQ, 90 or less; RBDSQ, 5 or more. 2) participants who don't have any non-motor symptoms: SCOPA-AUT, SAOQ, and RBDSQ scores are all normal. Exclusion criteria: Subjects who have mental and neurological disorders other than depression Subjects who are inappropriate to participate in the study
Full study name & original research details

Official study title

Prospective study on early diagnosis of Parkinson's disease in medical checkup examinees with non-motor symptoms - NaT-PROBE

Short title used by the registry

Prospective study on early diagnosis of Parkinson's disease in medical checkup examinees with non-motor symptoms

Original description

Intervention: Skin biopsy, MIBG scintigraphy and DaT scan Primary outcome: Incidence of Parkinson's disease during the 10 year follow-up period Secondary outcome: Changes in H/M ratio of MIBG scintigraphy during the 10 year follow-up period Changes in SBR of DaT scan during the 10 year follow-up period

Conditions reported: Parkinson's disease Dementia with Lewy Bodies

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Skin biopsy, MIBG scintigraphy and DaT scan
Phases
Not selected
Sponsor
Nagoya University, Department of Neurology
Start date reported by registry
2018-03-31 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-11 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Keita Hiraga · 052-744-2391 · hiraga.keita.n5@f.mail.nagoya-u.ac.jp

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Japan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.