Recruiting · registry status

Brain responses to sounds beyond hearing range

This study investigates whether sound frequencies people cannot hear affect brain activity and thinking.

Testing a treatment or activity · Study reference: JPRN-UMIN000015303

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported date): 2014-10-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 20years-old to 90years-old · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: male and female

Inclusion criteria: 1. Patients who meet criteria of major neurocognitive disorders by DSM-5 and have one caregiver (living with the patient at least ten hours a week). 2. Patients who meet criteria of major depresive disorder, schizophrenia, developmental disorder or Parkinson's disease. Exclusion criteria: 1. In case they show suicide attempt, excitement and violence. 2. In case they have history of developmental disorder, bipolar disorder or alchol/drug abuse. 3. In case they have hearing difficulties. 4. In case they meet a contraindication for MRI scan.

Full study name & original research details

Official study title

Cognitive and neurophysiological effects of inaudible sounds - Cognitive and neurophysiological effects of inaudible sounds

Short title used by the registry

Cognitive and neurophysiological effects of inaudible sounds

Original description

Intervention: Exposure of inaudible sounds Exposure of sounds without inaudible frequency ranges Primary outcome: Correlations between the structual characteristics of brain and changes in brain activities induced by inaudible sounds Secondary outcome: Correlations between the structual and functional characteristics of brain induced by inaudible sounds and the flowing items. 1. Scores of rating scales for neuropsychiatric symptoms, including HAM-D, MADRS, MMSE, BEHAVE-AD, NPI, MINI, BACS-J. 2. Scores of cognitive functions including executive functions (WCST, Uchida-Kraepelin (U-K) test), attention function (CPT, Go/NoGo task), working memory, and emotion recognition (facial expression identification/discrimination).

Conditions reported: Patients of dementia with behavior and psychological symptoms (BPSD), depression, schizophrenia, developmental disorder and Parkinson's disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

JPRN · JPRN-UMIN000015303 ↗ — Recruiting; WHO ICTRP processed 2026-06-29; checked 2026-10-14

Study type: Interventional
Interventions: Exposure of inaudible sounds Exposure of sounds without inaudible frequency ranges
Phases: Not applicable
Sponsor: National Center of Neurology and Psychiatry
Start date reported by registry: 2014-10-01 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Yuichi Yamashita · 042-346-1718 · yamay@ncnp.go.jp

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Japan

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.