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Famotidine for unwanted movements from levodopa

Researchers are testing whether famotidine changes involuntary movements associated with Parkinson's treatment.

Testing a treatment or activity · Study reference: IRCT20231016059737N2

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Start (reported date)
2025-10-22

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

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Who can join?

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Sex eligibility reported by registry: both

Inclusion criteria: parkinsonians patients who has developed levodopa induced dyskinesia.who has no previuos history of surgery for parkinson. Exclusion criteria: hypersensitivity to Famotidinliver failurerenal failureknown gastrointestinal diseasehistory of consumption of histamin receptor antagonist drugs in last 6 month
Full study name & original research details

Official study title

Evaluating the Effect of famotidine on levodopa induced dyskinesia in patients with Parkinson disease

Short title used by the registry

the Effect of famotidine on levodopa induced dyskinesia

Original description

Intervention: Intervention 1: Intervention group 1: recipients of famotidine (Shafa company) at a dose of 80 mg per day orally for three months. Intervention 2: Intervention group 2: recipients of famotidine (Shafa Company) at a dose of 120 mg per day orally for three months. Intervention 3: Control group: Placebo taken orally twice a day for three months. Produced by the Faculty of Pharmacy, Shiraz University of Medical Sciences. Primary outcome: Levodopa-induced dyskinesia measured by Parkinson and Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS). Timepoint: Check the Parkinson and Movement Disorder Society Unified Parkinson's Disease Rating Scale for Parkinson's Disease (MDS-UPDRS) before and three months after famotidine administration. Method of measurement: Parkinson and Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS).

Conditions reported: Condition 1: Parkinson's disease. Condition 2: drug induced dyskinesia. Parkinson's disease Drug induced subacute dyskinesia;G24.01

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Intervention 1: Intervention group 1: recipients of famotidine (Shafa company) at a dose of 80 mg per day orally for three months. Intervention 2: Intervention group 2: recipients of famotidine (Shafa Company) at a dose of 120 mg per day orally for three months. Intervention 3: Control group: Placebo taken orally twice a day for three months. Produced by the Faculty of Pharmacy, Shiraz University of Medical Sciences.
Phases
3
Sponsor
Shiraz University of Medical Sciences
Start date reported by registry
2025-10-22 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Vahid Reza Ostovan · +98 71 3612 1000 · ostovanv@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Iran (Islamic Republic of)

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.