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Atomoxetine for freezing while walking

This study tests a medicine to investigate episodes when a person with Parkinson's becomes unable to step forward.

Testing a treatment or activity · Study reference: IRCT20211008052695N1

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported date)
2021-09-23

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age range not listed · Ask the team who can join

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Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: 1) Diagnosis of Parkinson's disease based on examination and history 2) Patients with stage 2-4 of Hoehn and yahr scale; 3) Normal tests (vitamin B12, thyroid, liver, and kidney tests) 4) Levodopa treatment for at least 3 months before the study 5) Ability to walk at least 20 steps without the use of assistive devices Exclusion criteria:
Full study name & original research details

Official study title

Evaluation of Atomoxetine efficacy on Freezing of gait in patient with Parkinson

Original description

Intervention: Intervention 1: Intervention group: Group A includes 16 patients randomly selected by an uninformed person and treated with atomoxetine 40 mg for 2 weeks and then increase the dose to 80 mg for six weeks. Intervention 2: Control group: Group B includes 16 patients who are randomly selected by an uninformed person and are treated with a placebo similar to group A. Primary outcome: Freezing of gait in patient with Parkinson. Timepoint: Patients are treated with atomoxetine at a dose of 40 mg for 2 weeks and then increase the dose to 80 mg for six weeks. Method of measurement: The first visit will be on the first day and before starting treatment, determining the FOGQ questionnaire's score, and starting the medication. This questionnaire consists of 6 questions, each of which receives a score of 0 to 4, and the minimum score is 0, and the maximum is 24. The second visit will take place two weeks after the start of treatment, and the third visit will take place 6 weeks after the second visit.

Conditions reported: Parkinson disease. Secondary parkinsonism, unspecified;G21.9

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Intervention 1: Intervention group: Group A includes 16 patients randomly selected by an uninformed person and treated with atomoxetine 40 mg for 2 weeks and then increase the dose to 80 mg for six weeks. Intervention 2: Control group: Group B includes 16 patients who are randomly selected by an uninformed person and are treated with a placebo similar to group A.
Phases
3
Sponsor
Ahvaz University of Medical Sciences
Start date reported by registry
2021-09-23 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Seyed Ehsan Mohamadianinejad · +98 61 3320 4531 · D.R.ramezanirad@gmail.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Iran (Islamic Republic of)

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.