RESEARCH / PARTICIPATIONBack to the library
← Find a study
Recruiting · registry status

A liquorice extract alongside usual treatment

This study tests a plant extract and measures Parkinson's symptoms. Benefits remain to be established.

Testing a treatment or activity · Study reference: IRCT20120305009204N3

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

Open the official registry record ↗

Follow this study

Looking for volunteers

Start (reported date)
2018-02-04

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 30 years to 80 years · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: Age between 30 to 80 years idiopathic parkinson disease (PD) initiation of PD symptoms in recent 6 years The modified Hoehn and Yahr Scale: staging = 3 no treatment changes within 4 weeks before starting the intervention Exclusion criteria: Consumption of warfarin; selective serotonin reuptake inhibitors (SSRI), Monoamine oxidase inhibitors (MAOIs), or diuretic History of stroke; myocardial infarction; heart failure; renal failure or cardiac arrhythmia Uncontrolled hypertension and hypokalemia pregnant and lactating women Liver diseases Diabetes complication of treatment including urticaria, pruritis, nasea and vomiting and vertigo
Full study name & original research details

Official study title

Study of the effectiveness of polyphenol rich extract of licorice as an adjunct therapy on improving symptoms of patients with Parkinson disease

Short title used by the registry

Effect of polyphenol rich extract of licorice on improving symptoms of Parkinson disease

Original description

Intervention: Intervention 1: Intervention group: Treatment group will receive polyphenol rich extract of licorice at the dose of 136 mg/ 5cc syrup, twice a day for 6 months, in adjunct to the routine treatment of Parkinson disease. Intervention 2: Control group: The control group will receive placebo syrup at the same dose (5cc, twice a day for 6 months) in adjunct to the routine treatment of Parkinson disease. Primary outcome: Unified Parkinson’s Disease Rating Scale (UPDRS). Timepoint: First visit and every 6-8 weeks up to 6 months after intervention began. Method of measurement: Examination by the neurologist physician and Rating the diseases scale based on the Unified Parkinson's Disease Rating Scale (UPDRS). Secondary outcome: Patients electrolytes level. Timepoint: At the beginning of the study and every 6-8 weeks for six months after the intervention began. Method of measurement: Serologic tests.;Patients blood pressure. Timepoint: At the beginning of the study and every 6-8 weeks for six months after the intervention began. Method of measurement: Measurement by the physician with a blood pressure monitor.

Conditions reported: Parkinson disease. Parkinson's disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Intervention 1: Intervention group: Treatment group will receive polyphenol rich extract of licorice at the dose of 136 mg/ 5cc syrup, twice a day for 6 months, in adjunct to the routine treatment of Parkinson disease. Intervention 2: Control group: The control group will receive placebo syrup at the same dose (5cc, twice a day for 6 months) in adjunct to the routine treatment of Parkinson disease.
Phases
3
Sponsor
Shiraz University of Medical Sciences
Start date reported by registry
2018-02-04 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Dr. Azadeh Hamedi; Dr.Peyman Petramfar · +98 132424127 · hamediaz@sums.ac.ir

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Iran (Islamic Republic of)

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.