Recruiting · registry status

Using speech recordings to study thinking difficulties

Researchers are analysing speech in people with Parkinson's, Alzheimer's and other thinking conditions, alongside healthy volunteers.

Learning by observing or collecting information · Study reference: DRKS00034755

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Start (reported date): 2025-02-07

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No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

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Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Age 18 years and over · Ask the team who can join

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Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion criteria: Diagnosis of Alzheimer´s disease (AD), Parkinson’s disease (PD), vascular cognitive impairment (VCI) according to current national and international diagnostic criteria guidelines (S3 Demenz Leitlinien) Exclusion criteria: Inability to consent based on severity of cognitive impairment, as defined by a stage of moderate to severe dementia, defined by a Clinical Dementia Rating (CDR) total score >=2, according to clinical records. For the healthy (neurotypical) control group: history of past or current neurological or major psychiatric disorder, severe traumatic brain injury, alcohol or drug abuse.

Full study name & original research details

Official study title

Automatic processing of speech in cognitive disorders - AiXCog

Short title used by the registry

Automatic processing of speech in cognitive disorders

Original description

Intervention: Group 1: Patients with a diagnosis of Alzheimers disease, Parkinson's disease or vascular cognitive impairment as well as healthy control subjects will be included. After sufficient time for reflection and a signed declaration of consent, an examination consisting of a medical history and neuropsychological testing is carried out at Aachen University Hospital. Primary outcome: Use of automatically extracted natural language processing (NLP)-derived features from spontaneous speech to recognise cognitive impairment associated with Alzheimer's disease and related dementias (ADRDs). Secondary outcome: Characterise ADRDs using language features that differ significantly from those of neurotypical populations.

Conditions reported: F00 G20 F01;Dementia in Alzheimer disease;Parkinson disease;Vascular dementia

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

German Clinical Trials Register · DRKS00034755 ↗ — Recruiting; WHO ICTRP processed 2026-03-02; checked 2026-10-14

Study type: Observational
Interventions: Group 1: Patients with a diagnosis of Alzheimers disease, Parkinson's disease or vascular cognitive impairment as well as healthy control subjects will be included. After sufficient time for reflection and a signed declaration of consent, an examination consisting of a medical history and neuropsychological testing is carried out at Aachen University Hospital.
Phases: Not reported
Sponsor: Uniklinik RWTH Aachen
Start date reported by registry: 2025-02-07 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Kathrin Reetz · +49 241 80 89609 · kreetz@ukaachen.de

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Germany

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.