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Brain stimulation and control of movement and thinking

Researchers are using computer tasks to investigate how a brain area involved in movement influences decisions and actions.

Testing a treatment or activity · Study reference: DRKS00030402

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported date)
2023-03-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 80 years · Ask the team who can join

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Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion criteria: - Fluent in German - Between 18 and 80 years old - Capacity to consent and contract - Clinically established diagnosis of idiopathic Parkinson's syndrome - Existing bilateral implantation of subthalamic nucleus deep brain stimulation electrodes Exclusion criteria: - Instable, treatment-reliant psychiatric disease - Severe concomitant internal disease - Dementia - Withdrawal of consent
Full study name & original research details

Official study title

The Modulation of Motor-Cognitive Control by the Subthalamic Nucleus

Original description

Intervention: Group 1: Unimodal intervention: Parkinson patients who are treated with deep brain stimulation (DBS) are asked to fill in questionnaires and to carry out computer-based experiments ON and OFF stimulation. In more detail, the following procedures will be carried out: 1) different questionnaires regarding specifics of the patients Parkinson syndrome impairments and other psychiatric symptoms. 2) montage of the electro-encephalic (EEG) cap and recording of the exact electrode position via infrared-3-D scanner 3) regarding one of the computer-based experiments, the patients are asked to form probability-based decisions in order to reduce the risk of reducing their reward. This will last approx. 20 minutes. During this experiment, an EEG measurement will be recorded and, in case of an implanted PerceptTM neurostimulator, a simultaneous recording from the stimulation electrode will be registered as well. Experiment and measurement will be conducted once ON and once OFF stimulation. In addition, a video of the patients will be recorded with which the patients' movements are registered and can later be compared to the electrical signals. 4) regarding the other computer-based experiment, the patients are asked to press either a left or a right button with the index finger of the left or right hand, respecitvely. In preparation of the response (left or right button press), the patients are asked to use the information of a response cue that is presented earlier. This experiment will last approx. 50 minutes. During this experiment, an EEG measurement will be recorded and, in case of an implanted PerceptTM neurostimulator, a simultaneous recording from the stimulation electrode will be registered as well. Experiment and measurement will be cond Primary outcome: 1) Connectivity of cortical networks involved in motor prediction and conflict resolution Secondary outcome: 2) Standardized scores of the motor prediction task (cue validity and trial-specific conflict level) 3) Standardized scores of the decision-making task (approach rate and approach latency for different losing probabilities) 4) Psychometric measures

Conditions reported: Parkinson's disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Group 1: Unimodal intervention: Parkinson patients who are treated with deep brain stimulation (DBS) are asked to fill in questionnaires and to carry out computer-based experiments ON and OFF stimulation. In more detail, the following procedures will be carried out: 1) different questionnaires regarding specifics of the patients Parkinson syndrome impairments and other psychiatric symptoms. 2) montage of the electro-encephalic (EEG) cap and recording of the exact electrode position via infrared-3-D scanner 3) regarding one of the computer-based experiments, the patients are asked to form probability-based decisions in order to reduce the risk of reducing their reward. This will last approx. 20 minutes. During this experiment, an EEG measurement will be recorded and, in case of an implanted PerceptTM neurostimulator, a simultaneous recording from the stimulation electrode will be registered as well. Experiment and measurement will be conducted once ON and once OFF stimulation. In addition, a video of the patients will be recorded with which the patients' movements are registered and can later be compared to the electrical signals. 4) regarding the other computer-based experiment, the patients are asked to press either a left or a right button with the index finger of the left or right hand, respecitvely. In preparation of the response (left or right button press), the patients are asked to use the information of a response cue that is presented earlier. This experiment will last approx. 50 minutes. During this experiment, an EEG measurement will be recorded and, in case of an implanted PerceptTM neurostimulator, a simultaneous recording from the stimulation electrode will be registered as well. Experiment and measurement will be cond
Phases
N/A
Sponsor
Universität zu Köln
Start date reported by registry
2023-03-01 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Annika Sauter · 015227636593 · annika.sauter@uk-koeln.de

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Germany

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.