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Brain rhythms in Parkinson's and essential tremor

This study investigates patterns of brain activity and their relationship to movement disorders and stimulation treatment.

Testing a treatment or activity · Study reference: DRKS00017327

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported date)
2021-04-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 years to 80 years · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: all

Inclusion criteria: Patients undergoing deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) or posterior subthalamic area (PSA) for treatment of essential tremor (ET) Patients undergoing DBS of the subthalamic nucleus (STN), internal globus pallidus (GPi) or VIM with medically refractory tremor-dominant Parkinson's disease (PD) Selection by multidisciplinary teams consisting of neurologists, psychiatrists and functional neurosurgeons Patients must be able to give consent Exclusion criteria: Cognitive impairment (judge by interdisciplinary team) Intracranial bleeding, confusion, severe CSF leak, infection or any other complication after first stage of surgery Patients with accompanying severe medical or psychiatric disorders will also be excluded
Full study name & original research details

Official study title

Neuronal Oscillations in Parkinson Disease and Essential Tremor

Original description

Intervention: Group 1: Deep brain stimulation of the ventral intermediate nucleus (VIM) or posterior subthalamic area (PSA) in essential tremor (ET) or the subthalamic nucleus (STN), internal globus pallidus (GPi) or VIM in Parkinson's disease (PD). Primary outcome: Identify spectral changes in the LFP during and before the onset of tremor. Local field potentials will be recorded from externalized DBS leads between stage 1 and stage 2 surgery (either 1 or 2 days after lead implantation). We will use a TMSi Porti amplifier and custom-written software to record the time series signal. At a later stage, the time series signal will be pre-processed (filtered, detrended) and analysed (time-frequency decomposition) to examine changes in the time-frequency spectrogram related to tremor. Secondary outcome: Study the temporal dynamics of spectral changes related to tremor.

Conditions reported: G25.0 G20.0;Essential tremor;G25.0;G20.0

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Group 1: Deep brain stimulation of the ventral intermediate nucleus (VIM) or posterior subthalamic area (PSA) in essential tremor (ET) or the subthalamic nucleus (STN), internal globus pallidus (GPi) or VIM in Parkinson's disease (PD).
Phases
N/A
Sponsor
Klinik für Stereotaxie und Funktionelle Neurochirurgie Universitätsklinikum Köln
Start date reported by registry
2021-04-01 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Veerle Visser-Vandewalle · +49 221 478-82793 · veerle.visser-vandewalle@uk-koeln.de

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

Germany

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.