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Brain scans of the protective blood-vessel barrier

This study compares scans in people with and without Parkinson's to investigate changes in this barrier.

Learning by observing or collecting information · Study reference: ChiCTR2500100205

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported date)
2021-06-05

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 to 80 · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: 1.Meets the 2015 International Movement Disorder Society (MDS) clinical diagnostic criteria for clinically confirmed Parkinson's disease (PD); 2.Age >= 18, <= 80 years; 3.Disease duration of at least 1 year after PD was established; 4.The patient is capable of answering or cooperating in the administration of the series of scales or questionnaires involved in the study; the person or guardian is able and willing to sign the informed consent form; Exclusion criteria: 1.Allergy to contrast agents; 2.Individuals who cannot tolerate prolonged magnetic resonance imaging (MRI) examinations; 3.Diseases affecting blood-brain barrier permeability such as meningitis, cerebral small vessel disease, and Alzheimer's disease; 4.Researchers believe that individuals who are unable to complete the assessments and auxiliary examinations as required by the study protocol.
Full study name & original research details

Official study title

Blood-brain Barrier Permeability in Parkinson's Disease measured using Dynamic Contrast-enhanced Magnetic Resonance Imaging

Original description

Intervention: Parkinson 's disease group:None;Health control group:None; Primary outcome: Ktrans value of substantia nigra;UPDRS; Secondary outcome: MOCA;Hoehn-Yahr stage;MMSE;

Conditions reported: Parkinson's disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Observational
Interventions
Parkinson 's disease group:None;Health control group:None;
Phases
0
Sponsor
Zhujiang Hospital of Southern Medical University
Start date reported by registry
2021-06-05 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Shuzhen Zhu · +86 137 1915 3239 · 453951712@qq.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

China

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.