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Magnetic brain stimulation for unwanted movements

Researchers are testing repeated stimulation of two targets and measuring involuntary movement in Parkinson's.

Testing a treatment or activity · Study reference: ChiCTR2000037373

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

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Looking for volunteers

Start (reported date)
2020-10-01

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 40 to 75 · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: 1)Patients at age between 40 and 75 years old. 2) patients have been clinically diagnosed with PD according to the 2015 International MDS PD criteria. 3) patients whose symptoms have been well controlled in the condition of stable dopaminergic treatment for at least 1 month before the recruitment. 4) patients that have obvious dyskinesia (MDS-UPDRS-IV item 2 score is above 2 points and MDS-UPDRS-IV item 1 score is above 2 points). 5) patients or their legal guardians have agreed to participate the study and have signed the informed consent form. Exclusion criteria: 1) Pregnant or lactating women; 2) patients that have severe cognitive impairment or psychiatric symptoms; 3) patients that have severe liver and kidney impairment; 4) patients that have been participating the other clinical studies or participated other clinical studies within the previous 30 days at the recruitment; 5) patients that are unable to cooperate with the assessments; 6)patients with metal foreign bodies in the heads or pacemakers or cochlear implants.
Full study name & original research details

Official study title

A clinical study of dual target and multi course burst transcranial magnetic stimulation in the treatment of dyskensia in Parkinson' disease

Original description

Intervention: Intervention :TBS mode rTMS;control:TBSmode sham stimulation rTMS; Primary outcome: the difference value between the CAPSIT score at baseline and CAPSIT score after the initiation of the intervention; Secondary outcome: the difference value between the daily levodopa dosage and levodopa equivalent dosage at baseline and the daily levodopa dosage and levodopa equivalent dosage after initiation o the intervention;the difference value between the PD-NMSQ30 score at baseline and PD-NMSQ30 score after initiation o the intervention;the change between the activated brain areas and network at baseline and after the intervention;the change between the F18-FDG brain metabolism at baseline and the F18-FDG metabolism after the intervention;the association between the polymorphism of NMDA and BDNFgenes and the dyskinesia of PD;the difference value between the PDQ-8 score at baseline and the PDQ-8 score after intervention;the change between the tremor the parameters of the electromyography at baseline and the parameters of tremor electromyograhpy after intervention;the difference value between CGI score at baseline and CGI score after intervention;

Conditions reported: Parkinson 's disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Interventional
Interventions
Intervention :TBS mode rTMS;control:TBSmode sham stimulation rTMS;
Phases
0
Sponsor
Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine
Start date reported by registry
2020-10-01 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Zhenguo Liu · +86 21-25077501 · zhenguoliu2004@aliyun.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

China

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.