Recruiting · registry status

A probiotic for constipation and other symptoms

This study compares a gut bacteria preparation with placebo in people with Parkinson's.

Testing a treatment or activity · Study reference: ChiCTR1800016977

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Looking for volunteers

Start (reported date): 2018-07-15

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded

2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 50 to 80 · Ask the team who can join

These are starting points, not the full rules. The research team can tell you whether the study is right for your situation.

Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: 1. Patients diagnosed with PD according to the new MDS Clinical Diagnostic Criteria for PD and with Rome III criteria-confirmed constipation; 2. Patients between the age of 50-80 years; 3. No history of cardiac, renal, diarrhea, abdominal pain or hepatic conditions; 4. Agreed to drink study product during the study period; 5. Agreed to sign written informed consent; 6. Patients are aggred to record the diary information (ensure not to take other forms of probiotics and do not change the original constipation treatment drugs duing the study); 7. Stop drinking any probiotics in the 2 weeks prior to the study. Exclusion criteria: Ingestion of probiotics in the preceding 4 weeks; Use of antibiotics in the preceding 4 weeks; History of gastrointestinal disorders or surgery; Known or suspected allergy to probiotics; Comorbidities that prevent reliable completion of study assessments. Prior functional neurosurgery for PD or treatment with apomorphine infusion Recent initiation of dopaminergic medications in the preceding 3 months

Full study name & original research details

Official study title

A Randomized Double-Blinded Placebo-Controlled Trial for Bifidobacterium lactis M8 in the treatment of Parkinson's Disease's constipation and other non-motor symptoms

Original description

Intervention: 1:Bifidobacterium lactis M8;2:Placebo; Primary outcome: Bristol stool form scale;Depression;anxiety;

Conditions reported: Parkinson disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

ChiCTR · ChiCTR1800016977 ↗ — Recruiting; WHO ICTRP processed 2018-07-09; checked 2026-10-14

Study type: Interventional
Interventions: 1:Bifidobacterium lactis M8;2:Placebo;
Phases: Other
Sponsor: Weihai Municipal Hospital
Start date reported by registry: 2018-07-15 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

zhenguang Li · +86 18660388969 · drlizhenguang@163.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

China

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.