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Using different stimulation frequencies on each side

This study compares deep brain stimulation settings in people with Parkinson's.

Research study · Study reference: ChiCTR1800016522

Plain-language introduction written with AI from the registry; not independently checked by a clinician. Read the original details below ↓

This registry record was last updated over six months ago, or its update date is missing. Recruitment may have changed. Confirm with the team before making plans.

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Start (reported date)
2018-05-12

Planned dates can move. A study finishing does not tell us when a paper will be published.

No results summary has been confirmed in the registry records we imported. See connected papers below; we keep checking after recruitment ends.

Changes we have recorded
  • 2026-10-11 — recruiting

These are dates we observed a change, not necessarily the dates it happened.

Papers connected to this study

No connected paper has been found yet. The tracker checks the growing library for study identifiers and registry-linked publications.

Who can join?

Ages 18 to 65 · Ask the team who can join

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Read all the rules for taking part

Sex eligibility reported by registry: both

Inclusion criteria: 1. Idiopathic Parkinsons disease, in according with 2016 China diagnostic criteria for Parkinson's disease; 2. Levodopa Responsiveness improvement rate more than 30%; 3. Aged between 18-65 years old; 4. Medical Treatment is ineffective, even by further adjustment of therapeutic schedule; 5. Medical Treatment is effective, but patients can't bear the side effect within that dose (for example, severely disabling involuntary movement); 6. Dysfunction not responsive to medical treatment severely interferes with daily life; 7. patient or statutory guardian signs informed consent, with good compliance and cooperation with the follow-up. Exclusion criteria: 1. obviously affective disorder or phrenoblabia; 2. nervous system disease, such as epilepsy, brain trauma,brain tumor, severe cerebral infarction, alzheimer's disease, etc.; 3. people forbidden to MRI scan , for example with metal implantation materials; 4. All surgical contraindications (anticoagulants,terminal cancer, infectious disease and immuno-deficiency, etc.); 5. Pregnant or lactating women; 6. serve cognition impairment,incapable of cooperating with surgery and follow up; 7. Any situation endangering patient and it's successfully participation of the research program.
Full study name & original research details

Official study title

Bilateral differential frequency in subthalamic nuclues deep brain stimulation for Parkinson disease

Short title used by the registry

Bilateral differential frequency in subthalamic nucleus deep brain stimulation for Parkinson disease

Original description

Intervention: A:after activation of the implantable pulse generator,bilateral stimulation frequencies are set divergently(More than 30Hz difference) for 3 months,then set at the same level(same frequency number) for another 3 months;B:after activation of the implantable pulse generator,bilateral stimulation frequencies are set at the same level(same frequency number) for 3 months,then set at divergently(More than 30Hz difference) for another 3 months; Primary outcome: Unified Pakinson's Disease Rating Scale part II and III;Montreal cognitive assessment;Hamilto Anxiety;Hamilton Depression Scale;Unified Dyskinesia Rating Scale (UDysRS); Secondary outcome: 39-Item Parkinson's Disease Questionnaire;Minimum Mental State Examination;

Conditions reported: parkinson disease

Registry records for this study

Records are joined using registration identifiers. Titles alone do not establish that two studies are the same.

Study type
Not reported
Interventions
A:after activation of the implantable pulse generator,bilateral stimulation frequencies are set divergently(More than 30Hz difference) for 3 months,then set at the same level(same frequency number) for another 3 months;B:after activation of the implantable pulse generator,bilateral stimulation frequencies are set at the same level(same frequency number) for 3 months,then set at divergently(More than 30Hz difference) for another 3 months;
Phases
New Treatment Measure Clinical Study
Sponsor
Neurosuegery Department, West China Hospital, Sichuan University
Start date reported by registry
2018-05-12 (reported)

Registry updated: Not reported · Status last verified by the registry submitter: Not reported

Registry records retrieved 2026-10-14 (UTC). Individual records may have older updates. Recruitment and eligibility must be confirmed with the study team.

Contact the research team

Public study contacts supplied to the registry. Ask whether recruitment is still open and what participation involves.

Wang Wei · +86 18982078332 · 13808170699@126.com

Study locations

Site status can differ from overall study status. “Status not reported” means local availability needs confirmation. Remote participation and travel arrangements must be checked with the team.

Facility not reported

China

Status not reported

The original descriptions and participation rules come from the registry. Participation is voluntary and does not guarantee benefit.