Mô tả một số triệu chứng ngoài vận động ở người bệnh Parkinson giai đoạn trung bình và nặng tại Trung tâm Thần Kinh - Bệnh viện Bạch Mai / Descripton of some non- motor symtomps in parkinson’s desease patients in the moderrate and severe stages at Bach Mai Neurology Center
Mô tả một số triệu chứng ngoài vận động ở người bệnh Parkinson giai đoạn trung bình và nặng tại Trung tâm Thần Kinh - Bệnh viện Bạch Mai / Descripton of some non- motor symtomps in parkinson’s desease patients in the moderrate and severe stages at Bach Mai Neurology Center
Where did the research take place?
The study site has not been established. Author addresses may differ from where the research occurred.
A plain-language reading has not been prepared for this paper yet.
Original abstract
Parkinson's disease is a progressive neurodegenerative disorder. The disease is characterized by motor disturbances including bradykinesia, tremors, rigidity, and postural instability. The motor symptoms are mainly the result of the continuous death of dopaminergic neurons in the substantia nigra and the basal ganglia of the brain. Additionally, Parkinson's patients also experience non-motor disorders such as cognitive decline, autonomic dysfunction, sleep disturbances, urinary issues, depression, …Besides motor disturbances, non-motor disorders are very common and significantly impact the quality of life of Parkinson's patients. Proper attention to non-motor symptoms yields optimal treatment outcomes, especially in patients with moderate to severe stages.Objectives: To describe some non-motor disorders in patients with moderate and severe Parkinson's disease.Subjects and methods: A cross-sectional descriptive study on 93 patients with moderate and severe Parkinson's disease at the Neurology Center - Bach Mai Hospital from January 2025 to September 2025.Results: There were 41 female patients and 52 male patients with an average age of 65.11± 11.23 years old, mainly aged 61 - 70 years old (accounting for 44.2%): cardiovascular symptoms appeared. popular with 67.7% in the study group; Among sleep disorders, excessive daytime sleepiness accounts for the highest rate (85%), restless legs syndrome is less common (30.1%); Most of the patients in the study showed anxiety (96.8%) and depression (83.9%); The rate of psychotic symptoms in the study group was relatively low (7.5% hallucinations, 8.6% delusions); The majority of patients present with memory disorders (89.25%) and difficulty concentrating (87.1%); The most common digestive disorder is constipation (82.8%); The most common urinary disorder is nocturia (65.6); The least common symptom was urinary urgency (11%); Decreased libido is quite common in Parkinson's disease (90.4%) Conclusion: besides movement disorders, non-motor disorders appear very often and severely, doctors need to pay more attention to the problem. this topic in clinical practice.